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941
Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities
Published 2025-02-01“…Using comprehensive genome analysis, we compared the genome of L. fermentum SD7 with 153 available genome sequences of L. fermentum strains and categorized the 154 strains into six distinct clades based on core gene single nucleotide polymorphisms. Among the 12,598 orthologous proteins, we identified 910 core genes and 10,169 accessory genes. …”
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942
Valproic acid targets IDH1 mutants through alteration of lipid metabolism
Published 2024-08-01“…VPA inhibited the transcription of lipogenic genes and these lipogenic genes showed significant decreases in promoter chromatin accessibility only in the IDH1 MT glioma cell lines tested. …”
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943
Exploring biomarkers and molecular mechanisms of Type 2 diabetes mellitus promotes colorectal cancer progression based on transcriptomics
Published 2025-02-01“…The limma package was used to identify differentially expressed genes in tumor tissue from CRC patients with or without T2DM. …”
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944
Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context
Published 2025-03-01“…Using a deep learning model, we found 107 (81%) of the putative causal genes (41 novel genes) were predicted to interact with SARS-COV-2 proteins. …”
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945
RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients
Published 2024-10-01“…Data from The Cancer Genome Atlas, Gene Expression Omnibus, and Genotype-Tissue Expression identified 286 differentially expressed genes linked to polyamine pathways in breast cancer. …”
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946
Advances in personalized gastroenterology and hepatology 2016
Published 2016-08-01“…On the other hand, using high throughput array and other technologies, it is possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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947
Melanoma genomics – will we go beyond BRAF in clinics?
Published 2024-09-01“…We also present a comparison of genomic profiles obtained in recent years with a focus on the most common melanoma genes. Finally, we propose our melanoma gene panel consisting of 22 genes that, in our opinion, are “must-have” genes in both melanoma-specific genomic tests and pan-cancer tests established to improve the treatment of melanoma further.…”
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948
Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat
Published 2025-02-01“…Abstract Brain regions drive multiple physiological functions through specific gene expression patterns that adapt to environmental influences, drug treatments and disease conditions. …”
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949
Characterization and phylogenetic analysis of the chloroplast genome of endangered Impatiens chishuiensis
Published 2024-12-01“…It encodes a total of 120 genes, including 95 protein-coding genes, 8 rRNA genes, and 17 tRNA genes. (2) A total of 87 SSR sequences was detected. 20 327 codons were detected, with leucine (Leu) being the most abundant and tryptophan (Trp) being the least. (3) Impatiens was divided into two subgenera, including subg. …”
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950
Transcription factor A, mitochondrial promotes lymph node metastasis and lymphangiogenesis in epithelial ovarian carcinoma
Published 2025-02-01“…However, the mechanism of mitochondrial genes in epithelial ovarian cancer (EOC) remains unclear. …”
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951
Disorders in brassinosteroids signal transduction triggers the profound molecular alterations in the crown tissue of barley under drought.
Published 2025-01-01“…On the other hand, a set of genes expressed independently of the genotype was identified, including dehydrin encoding genes. …”
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952
INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES
Published 2018-08-01“…On the other hand, high throughput array and other technologies made it possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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953
An investigation of factors associated with antenatal care attendance in Gauteng in 2015
Published 2024-06-01“…The identified health and household factors should inform policies and programmes geared towards improving services around antenatal care provision. …”
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954
From data to diagnosis: leveraging deep learning in IoT-based healthcare
Published 2024-11-01“…The future of deep learning in healthcare IoT is geared toward enhancing data security, improving device integration, and creating patient-centric models through innovative technologies such as blockchain and edge computing. …”
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955
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956
Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq
Published 2025-01-01“…The candidate genes within this region include two genes related to heat shock proteins, three genes associated with pollen fertility, and four genes involved in heat stress and other abiotic stress responses. …”
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957
Caution when using network partners for target identification in drug discovery
Published 2025-04-01“…We assessed how accurately including interacting genes with the ExWAS-, Effector Index-, and GPS-selected genes identified positive controls, focusing on precision, sensitivity, and specificity. …”
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958
DNA methylation and its influence on the pathogenesis of osteoarthritis: a systematic literature review
Published 2025-02-01“…Results: We identified 23 gene-specific studies and 28 genome-wide methylation analyses. …”
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959
Perfluorooctane sulfonate (PFOS) induced bone loss by inhibiting FoxO1-mediated defense against oxidative stress in osteoblast
Published 2025-01-01“…Through transcriptome analysis, the differentially expressed genes (DEGs) were screened and the biofunctions were elucidated by Kyoto Encyclopedia of Genes and Genomes (KEGG) and The Gene Set Enrichment Analysis (GSEA). …”
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960
The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium
Published 2025-02-01“…Typhimurium and the mutant lacking the arcB gene exposed to NaOCl to describe the global transcriptional response. …”
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