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1001
Genomic insights and comparative analysis of Colletotrichum species associated with anthracnose fruit rot and crown rot of strawberry in North Carolina
Published 2025-02-01“…Colletotrichum is a large genus of fungal phytopathogens responsible for significant economic losses in numerous crops globally. …”
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1002
Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure
Published 2025-02-01“…Interrogation of temporal and signalling-specific gene expression in this atlas, evaluated against cell type-specific gene expression in human complex trait data highlights the WNT-inhibitor gene TMEM88 as a regulator of mesendodermal lineages influencing cardiovascular and anthropometric traits. …”
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1003
Morphological, physiological, element absorption, and transcriptomic analysis reveals the mechanism of 2-(3,4-Dichlorophenoxy) trimethylamine alleviating copper stress in cucumber...
Published 2025-01-01“…Transcriptome analysis showed that copper absorption, transport, detoxification genes, cell wall component related genes and nitrogen metabolism related genes played a crucial role. …”
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1004
Assembly of the salt-secreting mangrove Avicennia rumphiana.
Published 2025-01-01“…A total of 671 genes matched to genes that are linked to salt tolerance. …”
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1005
Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection
Published 2025-02-01“…We detected a subset of genes associated with the previously identified epithelioid (32 genes) and sarcomatoid molecular components (36 genes) in PM-EVs. …”
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1006
Population structure, selection signal and introgression of gamecocks revealed by whole genome sequencing
Published 2025-02-01“…A total number of fifteen shared candidate genes were identified using the three different detection strategies. …”
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1007
Genome-wide association study of the antibody response to <i>Corynebacterium pseudotuberculosis</i> in sheep
Published 2025-02-01“…The study revealed two suggestive SNPs (single-nucleotide polymorphisms) on chromosomes 11 and 20, with the most significant SNP in the first exon of the <i>TRIM16</i> (tripartite-motif-containing 16) gene. By analysing genomic alterations and their context between positive and negative animals, including a gene ontology (GO) analysis of genes within <span class="inline-formula">±</span> 500 kb regions of the suggestive SNPs, we identified genes and immune-related processes and pathways potentially influencing CLA susceptibility. …”
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1008
Nitidine chloride inhibits the progression of hepatocellular carcinoma by suppressing IGF2BP3 and modulates metabolic pathways in an m6A-dependent manner
Published 2025-02-01“…Through intersection analysis, we pinpointed 30 potential metabolic target genes regulated by NC through IGF2BP3. Based on the expression of these genes, the metabolic scores for each HCC patient were calculated. …”
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1009
GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease
Published 2025-02-01“…Subsequently, the expression of hub genes was validated using additional TBI- and PD-related GEO datasets and the Comparative Toxicogenomics Database (CTD). …”
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1010
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1011
Pancreatic Cancer: Current Concepts, Trends, and Future Directions
Published 2025-02-01“…Therefore, researchers and clinicians have geared up for the battle against PC. This review will systematically discuss recent developments in adjuvant, neoadjuvant, and palliative treatment modalities. …”
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1012
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1013
A biallelically active embryonic enhancer dictates GNAS imprinting through allele-specific conformations
Published 2025-02-01“…Abstract Genomic imprinting controls parental allele-specific gene expression via epigenetic mechanisms. Abnormal imprinting at the GNAS gene causes multiple phenotypes, including pseudohypoparathyroidism type-1B (PHP1B), a disorder of multihormone resistance. …”
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1014
Differential Diagnosis of MutYH-Associated Polyposis from Sporadic Colon Polyps
Published 2019-01-01“…Mutations in the MutYH gene were detected in 2 out of 18 patients having more than 100 polyps. …”
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1015
Methodical approaches in experimental modelling of non-alcoholic fatty liver disease
Published 2015-09-01“…In the first the liver of laboratory animals is the main pathogenic target, metabolic disorders develop insignificantly (lines of animals with of Acetyl-CoA oxidase gene deletion, knockoutmice for methionine-adenosyl transferases-1А gene and animals with deleted specific hepatic phosphatase and tensin homologue gene). …”
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1016
Characterization of G2/M checkpoint classifier for personalized treatment in uterine corpus endometrial carcinoma
Published 2025-02-01“…Methods Gene expression profiles and clinical feature data mainly came from the TCGA-UCEC cohort. …”
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1017
Molecular Characterization of Methicillin Resistant and Extended Spectrum ?-Lactamase Staphylococcus aureus Isolated from Burn Patients
Published 2020-12-01“…PCR based molecular technique was done for the bla genes related to ?- lactamase enzymes by the specific primers, as well as genes which related to reduced sensitivity to Vancomycin were detected. …”
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1018
Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species
Published 2025-02-01“…Results Here, we used a combination of fine-scale mapping and gene expression analysis to further investigate positional candidate genes on the X chromosome. …”
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1019
Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice
Published 2025-02-01“…However, the mechanism behind genetic mutations in the non-coding region of genes that affect epigenetic modifications remains unclear. …”
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1020
Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways
Published 2025-02-01“…Transcriptome analysis revealed significant differentially expressed genes (DEGs) and their Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, resulting in the identification of 10 hub genes involved in the apoptosis, autophagy, necroptosis, and ferroptosis signaling pathways. …”
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