Toxicity of Low-dose Graphene Oxide Nanoparticles in an in-vivo Wild Type of Caenorhabditis elegans Model by Ming-Hsien Tsai, How-Ran Chao, Jheng-Jie Jiang, Yu-Hsieh Su, Mariene-syne P. Cortez, Lemmuel L. Tayo, I-Cheng Lu, Hao Hsieh, Chih-Chung Lin, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Ching-Kai Su, Sen-Ting Huang, Wen-Li Hsu

“…In the examination of the longevity of nematodes, it was found that the lifespan of all GO NP-exposed worms was significantly shortened as compared to the untreated worms. Gene expression of sod-1, sod-3, and ctl-2 presented significantly higher induction folds in the exposed worms compared with the controls. …”
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Intrahospital dissemination of multidrug-resistant Acinetobacter baumannii at a teaching hospital in Northeast of Mexico by Samantha Villarreal-Cruz, Adrián Camacho-Ortiz, Samantha Flores-Treviño, Licet Villarreal-Treviño, Paola Bocanegra-Ibarias

“…After species identification by MALDI-TOF MS and PCR, antimicrobial susceptibility was determined by disk diffusion and microdilution methods, carbapenemase-encoding genes (OXA-23, -24, -51, and -58) were searched, and clonal diversity was analysed by PFGE and MLST. …”
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Gingival fibroblast suppress the osteogenesis process mediated by bone substitute materials via WNT/β-catenin signaling pathway in vitro and in vivo by Guanqi Liu, Jiahui Lin, Xiaoyan Chen, Runheng Liu

“…In vivo animal experiments were conducted to assess the effect of gingival fibroblasts on BSM-mediated bone regeneration.ResultsGingival fibroblasts and BSMs co-culture environment did not affect MMSCs proliferation but significantly inhibited ALP expression and activity, as well as osteogenic gene and protein expression, while promoting expression of fibrogenic markers. …”
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Understanding cancer from an evolutionary perspective: high-risk reprogramming of genome-damaged stem cells by Vladimir F. Niculescu

“…This shift is steered by genes housed within the ancestral genome compartment, pervasive across all metazoan genomes, encompassing humans, and governed by a premetazoic ancestral gene regulatory network. …”
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Pleiotropic effects of a recessive Col1a2 mutation occurring in a mouse model of severe osteogenesis imperfecta. by Michelangelo Corcelli, Rachel Sagar, Ellen Petzendorfer, Mohammad Mehedi Hasan, Fleur S van Dijk, Anna L David, Pascale V Guillot

“…In Europe, approximately 85-90% of individuals with Osteogenesis Imperfecta (OI) have dominant pathogenic variants in the Col1a1 or Col1a2 genes whilst for Asian, especially Indian and Chinese cohorts, this ratio is much lower. …”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…Together, our findings demonstrated that TCDD was teratogenic in numerous cranial neural crest cell-derived craniofacial bone development, and disrupted multiple genes for osteogenic differentiation via the TCDD-mediated AhR/ ERα signaling cross-talk.…”
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Efficient biosynthesis of β-caryophyllene by engineered Yarrowia lipolytica by Young-Kyoung Park, Lucie Studena, Piotr Hapeta, Ramdane Haddouche, David J. Bell, Pablo Torres-Montero, Jose Luis Martinez, Jean-Marc Nicaud, Adriana Botes, Rodrigo Ledesma-Amaro

“…Employing the same combination of promoters and genes in wild-type-based strain with two copies resulted in a 1.36-fold increase in β-caryophyllene. …”
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Impact of copper stress in the intestinal barriers and gut microbiota of Chinese stripe-necked turtle (Mauremys sinensis) by Zeeshan Ali, Ijaz Khan, Muhammad Shahid Iqbal, Haitao Shi, Li Ding, Meiling Hong

“…Furthermore, This study found that copper exposure increases gut permeability by suppressing tight junction genes and triggers an inflammatory response in the gut, as indicated by elevated inflammatory cytokines. …”
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CHOLINE TRANSPORTER-RELATED 4 (CTR4) Is Involved in Drought and Saline Tolerance in Rice by Yu Shicong, Luo Ruxian, Zheng Shuqin, Ning Jing, Shi Yuanzhu, Guo Daiming, Jia Liangmeng, Wang Sen, Xiao Guizong, Guo Pengwang, Li Yang, Ma Xiaoding

“…Using MutMap sequencing, we characterized the role of a choline transporter-related family gene, CTR4 (Choline Transporter-Related 4), in rice’s tolerance to drought and salt stress. …”
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Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity? by Simona Kurekova, Lucia Pavlikova, Mario Seres, Viera Bohacova, Jana Spaldova, Albert Breier, Zdena Sulova

“…Wolframin is an ER transmembrane protein, product of the WFS1 gene whose mutations are associated with Wolfram syndrome. …”
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CRISPR/Cas genome editing for cotton precision breeding: mechanisms, advances, and prospects by Vijay Sheri, Harikrishnan Mohan, Phanikanth Jogam, Anshu Alok, Gulab Khan Rohela, Baohong Zhang

“…Here we summarized the various target genes within the cotton genome which have been successfully altered with CRISPR/Cas tools. …”
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The Squash Bug, Anasa Tristis (Heteroptera: Coreidae): A Potential Greenhouse Pest of Beit Alpha Cucumber by Silvia I. Rondon, Daniel J. Cantliffe, James F. Price

“… The squash bug, Anasa tristis (DeGeer) (Heteroptera: Coreidae), is considered an important pest of cucurbits in open fields in the U.S. …”
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Development of a set of monosomic alien addition lines from Gossypium raimondii in Gossypium hirsutum toward breeding applications in cotton by Zhenzhen Xu, Xiaoxi Lu, Wenjie Ding, Wei Ji, Wuzhimu Ali, Heyang Wang, Shan Meng, Qi Guo, Peng Xu, Xianglong Chen, Liang Zhao, Huan Yu, Xinlian Shen

“…Abstract Background Gossypium raimondii Ulbr is a diploid wild cotton (2n = 26, D5D5) that originated in west-central Peru of South America and possesses desirable characteristics that are absent in the Upland cotton G. hirsutum. …”
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Case report: a rare case of hereditary colorectal cancer and brain tumor with café au lait spots in a child: constitutional mismatch repair deficiency (CMMRD) syndrome by Zubair Khurshid, Mishraz Shaikh, Tarek Talaat Harb Elkadi

“…Conclusions Hereditary cancers arising due to mismatch repair gene mutations cause early colorectal and brain cancers in children. …”
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Geschichte(n) jenseits von Helden und Siegern. Sammeln als solidarische Praxis bei Walter Benjamin und Ursula K. Le Guin by Carina Nagel

“… Im vorliegenden Artikel geht es um Walter Benjamins und Ursula K. Le Guins Kritik an Siegergeschichte und Heldengeschichten. …”
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Epigenetics of cancer drug resistance by Sayandeep Mukherjee, Ronit Dey, Subhabrata Guha, Nabendu Murmu, Gaurav Das

“…There are multiple evidences which suggest that malfunction of epigenetic regulation in functioning of a gene is directly related to the development of cancer. …”
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Value of medical genetic consultation at digestive organs diseases by T. V. Filippova

“…Detection of disorders of functioning of various genes and duly medical genetic consultation allow to carry out early diagnostics, choose optimum mode of treatment and prevent diseases of GIT.…”
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Geschichte(n) jenseits von Helden und Siegern. Sammeln als solidarische Praxis bei Walter Benjamin und Ursula K. Le Guin by Carina Nagel

“… Im vorliegenden Artikel geht es um Walter Benjamins und Ursula K. Le Guins Kritik an Siegergeschichte und Heldengeschichten. …”
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Unterwegs zu heiligen Orten – alte und neue Wallfahrtskritik im Christentum als Inspiration für die Pilgerpastoral by Michaela C. Hastetter

“… Angesichts der Pilgerschaft als religiösem Phänomen in den drei große monotheistischen Religionen geht die Autorin der Pilgerkritik in den Schriften der frühen Kirchenväter nach. …”
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GMNN and DLL1 mutation-related spondylocarpotarsal synostosis: a case report by Joonhwan Lee, Byungju Ryu, Yunhee Kim, Eunyoung Lee

“…To the best of our knowledge, this is the first report on the association of SCTS with these genes.…”
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