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1561
Role of exercise on ncRNAs and exosomal ncRNAs in preventing neurodegenerative diseases: a narrative review
Published 2025-02-01“…Non-coding RNAs (ncRNAs) and exosomal ncRNAs associated with vesicles have been recognized as influencers of gene expression and cell signaling, potentially contributing to the positive impact of physical activity on neurodegenerative conditions. …”
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1562
Extreme-phenotype genome-wide association study (XP-GWAS) of powdery mildew race 2 W tolerance in the USDA Citrullus germplasm collection
Published 2025-02-01“…Sources of powdery mildew tolerance were previously identified by screening the USDA Citrullus germplasm collection with P. xanthii races 1 W and 2 W. However, not all gene loci associated with tolerance to race 2 W have been identified and markers tightly linked to such loci have not been developed. …”
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1563
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
Published 2007-07-01“…FimH-mediated bacterial invasion of host bladder cells is inhibited by beta1 and alpha3 integrin-specific antibodies and by disruption of the beta1 integrin gene in the GD25 fibroblast cell line. Phosphorylation site mutations within the cytoplasmic tail of beta1 integrin that alter integrin signaling also variably affect UPEC entry into host cells, by either attenuating or boosting invasion frequencies. …”
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1564
Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality
Published 2025-02-01“…The bacterial composition exhibited significant similarity in the rhizosphere in the dry season and the endosphere in the wet season. Bacterial genes in the rhizosphere-rhizoplane were associated with environmental information processing, transportation and metabolism, while those in the rhizoplane-endosphere primarily handle metabolic processes. …”
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1565
Genetic variability and heritability estimates among nutritional traits of groundnut breeding lines
Published 2023-05-01“…Nonetheless, high heritability accompanied by high genetic advance as percent of mean for zinc (Zn) and iron (Fe), indicated that the heritability of these traits is due to additive gene effect and selection for such traits may be effective and rewarding.…”
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1566
Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis
Published 2025-02-01“…Here, we profiled thyroid in situ protein alterations in fine-needle aspiration biopsy samples from SAT patients using proteomic analysis and uncovered 57 differentially abundant proteins. Gene ontology and KEGG enrichment analyses identified that these proteins were enriched in processes involving infection, inflammatory response and cell adhesion and junction, which likely contribute to the pathogenesis. …”
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1567
Amine modified sodium alginate: Synthesis, characterization and in vivo evaluation in rainbow trout (Oncorhynchus mykiss)
Published 2025-03-01“…Alginate becomes an adequate option as a diet improver or drug/gene carrier through chemical modification processes and changes in its structure. …”
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1568
Nöro Pazarlama, Bilinçaltı Algı Ve Gösterge Bilimsel Çercevesinden “Hz. Muhammed: Allahın Elçisi” Sinema Filminin Çözümlemesi Ve Anlamlandırma
Published 2021-05-01“…Bilinçaltına seslendiği için etkisi diğer mesajlardan daha hızlı olan subliminal mesajların var olduğu savı –hâlâ tartışılsa da- geniş kitlelerce kabul edilmektedir. Görsel, işitsel, cinsellik, çarpıtma, yalan bilgi, gerçek üstü unsurlar ve millî duyguları yıpratan olumsuz mesajlar bilinçaltı ikna yöntemleri ile gizlenmektedir.Bu çalışmada önce nöropazarlama kavramı üzerine durulmuş ardından algı ve önemi paylaşılmış sonra üzerinde tartışmaların devam ettiği sublimal algı ve filmler konusu ele alınmış ardından da Hz. …”
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1569
CircWDR78 inhibits the development of colorectal cancer by regulating the miR-653-3p/RGS4 axis
Published 2025-02-01“…We also used RNA-seq technology to explore the signal pathways and genes it might regulate. Finally, the luciferase assay and qRT-PCR experiment proved that circWDR78 could sponge miR-653-3p, and confirmed that RGS4 is the downstream target of miR-653-3p. …”
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1570
Multiple machine learning-based integrations of multi-omics data to identify molecular subtypes and construct a prognostic model for HNSCC
Published 2025-02-01“…Methods We integrated four HNSCC datasets (TCGA-HNSCC, GSE27020, GSE41613, and GSE65858) from TCGA and GEO databases. Using 10 multi-omics consensus clustering algorithms via the MOVICS package, we identified two molecular subtypes (CS1 and CS2) and validated their stability. …”
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1571
Direct and Indirect Methods for Studying Human Gut Microbiota
Published 2022-08-01“…Trimethylamine N-oxide (TMAO) levels in the blood plasma and urine can also reflect the presence of specific bacterial clusters containing genes Cut, CntA/CntB and YeaW/YeaX. Therefore, further studies are required to reveal possible correlations between certain disorders and such parameters as the composition of gut microbiota, dietary patterns and TMAO concentration. …”
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1572
2023 Cumhurbaşkanlığı Seçim Sürecinde Siyasal Söylem: Meral Akşener Örneği
Published 2024-06-01“…Siyasal iletişim sürecinde, siyasal aktörlerin ideolojik bir söylem geliştirmesi ve bunun geniş kitlelere yayılması noktasında çok çeşitli iletişim ortamlarından ve yöntemlerinden faydalanması söz konusudur. …”
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1573
Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting
Published 2025-02-01“…At the same time, other innovative solutions were used for testing, such as repurposing tuberculosis GeneXpert diagnostic platforms to increase access to testing at points-of-care and introducing antigen rapid diagnostic tests for hard-to-reach communities. …”
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1574
Studying the impact of chitosan salicylaldehyde/schiff base/CuFe2O4 in PC3 cells via theoretical studies and inhibition of PI3K/AKT/mTOR signalling
Published 2025-02-01“…The mRNA expression levels of PI3K, AKT, mTOR, and CCND1 were examined in PC3-treated cells by using QRT-PCR, and the results demonstrated that, by down-regulating the expression levels of these genes, chitosan salicylaldehyde/CuFe2O4 significantly affected prostate cancer cell proliferation, progression, and autophagy more than chitosan salicylaldehyde. …”
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1575
Doğal Afetlerde Gazeteciler ve Travma Deneyimleri
Published 2022-12-01“…Doğal afetler, gazetecilerin travmatik stres düzeylerinin incelendiği ve ağırlıkla geniş örneklem gruplarıyla gerçekleştirilmiş çalışmalarda gazetecilerin en sık maruz kaldığı travmatik olaylardan biri olarak öne çıkmaktadır. …”
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1576
Spherical harmonics texture extraction for versatile analysis of biological objects.
Published 2025-01-01“…The Spherical Texture extraction characterizes biologically defined gene expression patterns in Drosophila melanogaster embryos, giving a quantitative read-out for pattern formation. …”
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1577
Exploring molecular disparities of H-type vasculature endothelial cells in osteonecrosis of the femoral head through single-cell analysis
Published 2025-02-01“…Molecular differences were assessed using Gene Ontology and KEGG analysis. Hypoxia, ferroptosis, pyroptosis, and parthanatos indices were calculated, and transcription factors were predicted using SENIC. …”
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1578
Options of dyslipidemia treatment at non-alcoholic fatty liver disease
Published 2018-08-01“…These substances play important role in lipid metabolism regulating expression of the genes (including PPARα) involved in lipid and glucose metabolism. …”
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1579
EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma
Published 2025-02-01“…It was verified that high EDF1 expression in NB cells led to Lactosylceramide (LacCer) accumulation, as well as downstream ganglioside-GD3, which subsequently increased the expression of CD52 and immune checkpoint genes, chemotaxis, and apoptosis-related events in activated CD8+T cells. …”
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1580
Potential links between human bloodstream infection by Salmonella enterica serovar Typhimurium and international transmission to Colombia.
Published 2025-01-01“…Typhimurium isolates was driven by horizontal gene transfer. Three ST313 isolates that caused bloodstream infection in Colombia were identified. …”
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