Anticancer effects of PEP06 (TB01) in combination with Trifluridine/Tipiracil (TAS-102) in a xenograft model of human colorectal cancer by Ruohong Lin, Jiaxing Cheng, Jinlong Zhao, Liang Zhou, Jian Li, Xinchun Yang

“…Methods This study utilized the human CRC HCT-116 xenograft nude mouse model to evaluate the antitumor effects of TAS-102 and TB01, both as mono-therapies and in combination therapies. Results The combination therapy not only demonstrated significantly inhibited tumor growth in a dose-dependent manner, but also seems to reduce the common toxicity associated with such treatments, as shown by the maintenance of body weights in the treated mice. …”
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DeepCERES: A deep learning method for cerebellar lobule segmentation using ultra-high resolution multimodal MRI by Sergio Morell-Ortega, Marina Ruiz-Perez, Marien Gadea, Roberto Vivo-Hernando, Gregorio Rubio, Fernando Aparici, Maria de la Iglesia-Vaya, Gwenaelle Catheline, Boris Mansencal, Pierrick Coupé, José V. Manjón

“…Unlike current tools that operate at standard resolution (1 mm3) or using mono-modal data, the proposed method improves cerebellum lobule segmentation through the use of a multimodal and ultra-high resolution (0.125 mm3) training dataset. …”
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Di (2-ethylhexyl) phthalate reduces sperm motility by decreasing sperm tail energy supply by Xiao-lu Li, Qi-meng Li, Yuan-zhuo Zheng, Die Hu, Xiao-yue Cai, Ke Yin, Yin-yin Qi, Zi yu Cheng, Xia Ning, Yang Cai, Wei Wu, Ting-yuan Lin, Tao Xu, Ling-li Zhao

“…The results of HPLC-MS/MS showed that DEHP metabolites were transported to the testes and epididium, indicating that MEHP (Mono-2-ethylexyl phthalate) could directly affect the espermatozoa of mature. …”
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Multicultural heritage in historical towns: the problems of conservation and interpretation by Rasa Čepaitienė

“…The relationship of such a multipartite problem with the cultural politics of modern Lithuania is examined. Two attitudes, mono-perspective (nationalistic) and multi-perspective (postmodern), towards the relation of ethnic communities and prevailing culture are distinguished. …”
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Actitud del académico hacia la promoción de la Ley de Servicio Comunitario del Estudiante Universitario by Filiberto Martins, María A Cabeza, Agatina Cammaroto, Luz Neris

“…La información se obtuvo mediante la aplicación de un cuestionario, a una muestra constituida por 56 unidades de análisis que constituyen el 15% de los académicos de la Universidad Simón Bolívar, Sede Litoral. Las condiciones reales del académico presentan aspectos mejorables en sus ámbitos profesional y pedagógico, laboral y cultural para su cónsone desenvolvimiento en su desempeño y en su rol como agente socializador, actitud reflexiva que incide en la responsabilidad y ética que se le atribuye al contexto legal de la Ley de Servicio Comunitario. …”
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Unveiling polyoxometalate redox properties at the nanoscale by Volatron, Florence, Izzet, Guillaume, Vuillaume, Dominique,  Proust, Anna

“…They undergo successive, reversible, and highly adjustable mono- (or multi-) electronic reduction processes within a narrow range of potentials. …”
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Video or audio listening tests for English language teaching context: which is more effective for classroom use? by Clara Herlina Karjo, Menik Winiharti, Safnil Arsyad

“…This study explored the extent to which multimodal testing materials can be used in testing listening comprehension for EFL students and how the results would differ from that of mono modality testing materials. The participants were 100 students of the English Department, Bina Nusantara University (henceforth Binus) University Jakarta. …”
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The value of common blood parameters for the differential diagnosis of respiratory tract infections in children by Jun’e Ma, Ting Tian, Nianyi Zeng, Yue Gu, Xuewei Ren, Zhengjiang Jin

“…However, common blood tests is simple and efficient, Therefore, the purpose of this study is to preliminarily distinguish Mycoplasma pneumoniae and influenza A virus infection in children by analyzing the results of common blood tests, thereby guiding clinical diagnosis and treatment.The results showed that, compared with children in the influenza A virus-positive group, children in the Mycoplasma pneumoniae-positive group had higher white blood cell (WBC), red blood cell (RBC), haemoglobin (HGB), platelet (PLT) counts, lymphocyte (LYM) and eosinophil (EOS) counts and ratios, as well as higher concentrations of C-reactive protein (CRP) and serum amyloid A (SAA), while neutrophil (NEU) and monocyte (MONO) counts and ratios, Neutrophil to Lymphocyte ratio( NLR) were lower, in addition, LYM, EOS counts and ratios, and NLR were all more effective in differentiating between the two pathogen infections, A combined analysis of these indicators further improved the differentiation efficacy. …”
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Toluene Conversion by Using Different Morphology MnO2 Catalyst by Huaijian Wang, Fangtong Liu, Wenting Yang, Chenglong Yu, Huanhuan Xiong, Jiaqi Li, Meijuan Lu

“…MnO2 with different morphology (nanotube, nanowire, nanocubic and nanoflower) were synthesized by hydrothermal method using KMnO4 and MnSO4 as precursors. Firstly, their structures were studied by X-ray diffraction (XRD), N2 adsorption desorption curve, H2 temperature programmed reduction (H2-TPR) and X-ray electron spectroscopy (XPS). …”
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Atmospheric Polychlorinated Naphthalenes in a Tropical Megalopolis of Vietnam: Concentrations, Potential Sources, and Health Risk by Ngo Thi Thuan, Nguyen Duy Dat, Nguyen Minh Ngoc, Nhung Thi-Tuyet Hoang, To Thi Hien, Moo Been Chang

“…Two typical homologue profiles were found in ambient air samples, including low-chlorinated PCNs (monoCNs > diCNs > triCNs) and medium-chlorinated PCNs (tetraCNs > triCNs). …”
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A molecular basis for spine color morphs in the sea urchin Lytechinus variegatus by Maria Wise, Madison Silvia, Gerardo Reyes, Rushane Dunn, Thomas M. Onorato, Cosmo Pieplow, Aidan Furze, El Hebert, Nathalie Oulhen, Dan Ritschoff, David R. McClay, Gary Wessel

“…The abundance of mRNAs encoding flavin mono-oxygenase variancts and polyketide synthase was predictive of the color of the adult and antibodies identified their histological location in the spine cells. …”
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Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response by Sophie C. van der Horst, Leonie Kollenstart, Amandine Batté, Sander Keizer, Kees Vreeken, Praveen Pandey, Andrei Chabes, Haico van Attikum

“…Mechanistically, we show that Lge1 affects replication initiation and/or fork stability by promoting Bre1-dependent H2B mono-ubiquitylation. Rox1 affects replication fork progression by regulating S-phase entry and checkpoint activation, hinging on cellular ceramide levels via transcriptional repression of SUR2. …”
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Preparación para la jubilación: diseño de un programa de acompañamiento psicológico by María Emilia Guevara Estacio

“…Para tal fin el estudio se efectuó en la Universidad Simón Bolívar Sede del litoral, entre septiembre y diciembre de 2009. desde el punto de vista metodológico es una investigación proyectiva apoyada con una investigación de campo. …”
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TockyPrep: data preprocessing methods for flow cytometric fluorescent timer analysis by Masahiro Ono

“…Conclusions: TockyPrep is available for distribution via GitHub at https://github.com/MonoTockyLab/TockyPrep , providing tools for data preprocessing and basic visualization of Timer fluorescence data. …”
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Laboratory diagnostics of alcohol intoxication in patients with alcohol-induced liver disease by A. I. Pavlov, A. I. Khazanov

“…In 56 patients (54,4%) asialoglycoside transferrin was studied, in 47 (45,6%) – all spectrum of sialoglycoside transferrin deficiency: a-, mono-, bi- and three- sialotransferrin deficiency.Results. …”
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Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis by Salvatore Dimonte, Paywast Jamal Jalal, Hiwa Abdulrahman Ahmad, Safa Bakr Karim, Taib Ahmed Hama Soor, Salar Ibrahim Ali, Muhammed Babakir-Mina, Francesco Greco

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Primary Fallopian Tube Carcinoma: Results of a Single-Institutional Retrospective Analysis of 17 Patients with Evaluation of Staging and Prognostic Factors by Neserine Tounsi, Hanen Bouazize, Ikram Margheli, Nadia Boujelbene, Hechiche Monia, Maher Slimane, Khaled Rahel

“…Our study aimed to review the managing process of primary carcinoma of the fallopian tubes in the mono-center institute and to identify prognostic factors impacting survival. …”
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Parámetros de calidad de carne de bondiolas de cerdo comercializadas en la provincia de La Pampa by Vanina Nerea Murcia, Micaela Stazionati, Adriana Pordomingo, Florencia Cora Jofre, Marianela Savio

“…El promedio de ácidos grasos saturados fue de 38,1 ± 2,38%. Los ácidos grasos mono- insaturados representan el 39,8 ± 3,57%. Los ácidos grasos poliinsaturados representan el 6,59 ± 0,97% del perfil de ácidos grasos. …”
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In-silico tool based on Boolean networks and meshless simulations for prediction of reaction and transport mechanisms in the systemic administration of chemotherapeutic drugs. by Fabián Mauricio Vélez Salazar, Iván David Patiño

“…Different combinations of E (0 kV/m, 46 kV/m, 70 kV/m), λinl (1x10-4m/s, 1x10-3m/s, 1x10-2m/s) and PK (One-short tri-exponential, mono-exponential) are examined. In general, results show that both the presence and relative importance of RTMs can differ between both PKs for a given combination of E and λinl. …”
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Catalytic Conversion for Hydrogen Sulfide by Xiaoyu Zhou, Xiaoning Pei, Rui Wang, Tiansheng Zhao

“…Abstract In this study, a series of transition metal mono-substituted heteropoly compounds H7PMo11MO39 (M = Co2+, Mn2+, Ni2+ and Zn2+) (HPMo11M) and single-absent heteropoly compounds H3PMo11O39 (HPMo11) were prepared for highly effective removal of hydrogen sulfide (H2S) from gas stream. …”
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