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1041
Changes in alcohol consumption among Belgian adults participating in the internet-based one-month-abstinence campaign ‘Tournée Minérale’
Published 2025-02-01“…In addition, moderating effects of age, sex, education level, successfully refraining from alcohol during TMC, risk drinking, drinking levels and binge drinking were investigated. Methods TMC is a fully automated mass media prevention campaign challenging Belgian adults to refrain from alcohol during the month February. …”
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1042
Innovations in Medical Education in Gastrointestinal Surgery Using Interactive Anatomical Tables
Published 2024-12-01“…Traditional education based on dissection materials cannot fully provide for the massive training of students, as biological materials cannot be restored or preserved and are quickly damaged. 3D models are devoid of these limitations.Aim: to evaluate the effectiveness of digital dissection in the educational trajectory of clinical anatomy using interactive anatomical tables and the need of students for the active use of these aids.Materials and methods. …”
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1043
Peripheral mitochondrial transplantation alleviates diabetes-associated cognitive dysfunction by suppressing cuproptosis
Published 2025-03-01“…However, the precise mechanism underlying its therapeutic effects are not fully elucidated. Given that imbalances in copper homeostasis and cuproptosis are associated with various neurodegenerative disorders and diabetic myocardial damage, we hypothesize a role for cuproptosis in the pathogenesis of DACD. …”
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1044
Health and social care use, costs, and satisfaction among key workers accessing Resilience Hub support during the COVID-19 pandemic
Published 2025-02-01“…Satisfaction was high, with median helpfulness rated 92 (out of 100), and many stating that Hubs either fully (148/299, 49.5%) or partially (54/299, 18.1%) met their needs. …”
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1045
CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma
Published 2022-03-01“…Transcriptomic analysis confirmed reduction in Foxp3 on addition of anti-CD25 to HSV/BRAFi, as well as increases in expression of genes reflecting interferon signaling and cytotoxic activity.Conclusions Combination HSV/BRAFi is an immunogenic therapy for BRAF mutant melanoma, but cannot fully control tumors. Dual therapy results in changes in T cell dynamics within tumors, with relatively maintained antigen signaling in Treg compared with conv CD4+. …”
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1046
PCSK9 affects vascular senescence through the SIRT1 pathway
Published 2025-03-01“…However, the mechanism underlying vascular injury is not fully understood. In the present study, the effect of proprotein convertase subtilin-type kexin 9 (PCSK9) inhibitors on the senescent state of human umbilical vein endothelial cells (HUVECs) and on senescent mice and lipopolysaccharides (LPS) were assessed. …”
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1047
EGFR inhibition augments the therapeutic efficacy of the NAT10 inhibitor Remodelin in Colorectal cancer
Published 2025-02-01“…Consequently, an integrated transcriptomic analysis is necessary to fully elucidate the role of NAT10-mediated ac4C modifications in CRC progression. …”
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1048
UPAYA MENINGKATKAN HASIL BELAJAR DAN KETERAMPILAN PROSES SAINS MELALUI MODEL PEMBELAJARAN BERBASIS MASALAH MENGGUNAKAN VIDEO PEMBELAJARAN PADA MATERI FLUIDA STATIS
Published 2020-09-01“…Subjek dalam penelitian ini adalah seluruh siswa kelas XI IPA 1 SMAN 10 Kota Ben gkulu yang berjumlah 28 orang. Hasil penelitian ini menunjukan bahwa hasil belajar siswa pada siklus I daya serapnya sebesar 75,89% dan ketuntasan belajar siswa sebesar 64,28% (belum tuntas) serta nilai rata-rata sebesar 75,89, meningkat pada siklus II daya serapnya sebesar 79,64% dan ketuntasan belajar siswa sebesar 78,57% (belum tuntas) serta nilai rata-rata sebesar 79,64, kemudian meningkat kembali pada siklus III daya serapnya sebesar 84,11% dan ketuntasan belajar siswa sebesar 89,29 (tuntas) serta nilai rata-rata sebesar 84,11, dan meningkat lagi pada siklus IV daya serapnya sebesar 88,57% dan ketuntasan belajar siswa sebesar 100 (tuntas) serta nilai rata-rata sebesar 88,57. …”
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1049
Designing a Model for Implementing Digital Banking Policy Based on Using Big Data in Iranian Banking Industry
Published 2024-11-01“…The results demonstrate that Big Data Management, along with associated governance, regulatory practices, and infrastructural considerations, are crucial categories that must be meticulously observed and integrated into the operational frameworks of state banks to fully harness the potential of big data.…”
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1050
Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans
Published 2024-08-01“…Only when direct effects are disentangled from those driven by peripheral confounds can TUS fully realize its potential for research and clinical applications.…”
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1051
Pengukuran Kapabilitas Tata Kelola TI Sistem Informasi Tiras dan Transaksi Bahan Ajar Universitas Terbuka Menggunakan Cobit 5
Published 2021-10-01“…It can be shown that the organization has not fully implemented some best practices for the process being evaluated, even there are already IT governance service standards but it has not been implemented optimally. …”
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1052
Enhancing deep learning methods for brain metastasis detection through cross-technique annotations on SPACE MRI
Published 2025-02-01“…HAQ alone achieves about 40% of the performance improvements seen with SPACE images as input, allowing for fast and accurate, fully automated detection of small (< 1 cm) BMs. …”
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1053
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy
Published 2022-03-01“…To mimic the feature of T-cell receptor (TCR) that recognizes the complex of major histocompatibility class I and peptide on the cell surface derived from the processed intracellular antigen, we used NY-ESO-1, a cancer-testis antigen, to develop a TCR-like fully human IgG1 antibody and its derivative, CAR-T cells, for cancer immunotherapy.Methods Human single-chain variable antibody fragment (scFv) phage library (~10∧11) was screened against HLA-A2/NY-ESO-1 (peptide 157–165) complex to obtain target-specific antibodies. …”
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1054
Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set...
Published 2025-01-01“…The male reproductive toxicity (MRT) from exposure to DEHP and its main metabolite, mono(2-ethylhexyl) phthalate (MEHP), has been well documented. Fully elucidating its toxic mechanism and discovering effective antagonists are desirable means to reduce the health risks of DEHP. …”
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1055
Efficacy of the internet-based intervention “Cultivating our resilience” (CORE) for improving resilience and coping strategies in university students: A randomized controlled trial...
Published 2025-03-01“…(Differences post-BL: d = 0.25, p = .0123; 6 M-BL: d = 0.16, p = .1505; 12 M-BL: d = 0.13, p = .1835).Adherence to fully complete the intervention was approximately 59 %.In conclusion, our study revealed promising outcomes for the CORE program, indicating its efficacy. …”
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1056
Strategies of physiological, morpho-anatomical and biochemical adaptation in seedlings of native species exposed to mining waste
Published 2025-01-01“…The seed germination of L. cuneifolia, B. retama, and P. tetracantha was fully inhibited in 100 % contaminated soil. Toxicological endpoints as NOEC, LOEC and IC50 ranged from 10 % to 25 % of soil contaminated with mining waste. …”
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1057
Penerapan Mekanisme Continuous Deployment dalam Pengembangan dan Pembaruan Perangkat Lunak Sistem Benam Berbasis Internet of Things
Published 2022-06-01“…The test results show that services on AWS can be interconnected and integrated with Jenkins and ESP32 so that they can update code from GitHub to three ESP32s with a fully automated process. The average time it takes to perform an update is only 63.5 seconds. …”
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1058
Search for lepton number violating decays of D s + $$ {\textrm{D}}_{\textrm{s}}^{+} $$ → h − h0e+e+
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1059
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1060
Evaluating the impact of a tertiary multidisciplinary meeting in metastatic breast cancer: A prospective study
Published 2025-02-01“…Follow up data was collected for 77 presentations; 65 (84.4 %) were fully implemented. 42 presentations resulted in high impact recommendations, of which 39 were implemented (92.6 %) (p = 0.005). …”
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