Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance. by Magdalena Widziolek, Anna Mieszkowska, Magdalena Marcinkowska, Bartlomiej Salamaga, Justyna Folkert, Krzysztof Rakus, Magdalena Chadzinska, Jan Potempa, Graham P Stafford, Tomasz K Prajsnar, Craig Murdoch

“…In contrast to the wild-type (W83) Pg, isogenic gingipain-null (ΔK/R-ab) or wild-type Pg treated with gingipain inhibitors caused less zebrafish mortality, bacteria were rapidly phagocytosed, acidified in phagosomes and eradicated when systemically injected, showing that gingipains are instrumental in preventing phagocytosis and intracellular killing of Pg by innate immune cells. …”
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Implementasi Sistem Peramalan Pengadaan Kebutuhan Bahan Baku Pangan Dengan Metode Weighted Moving Average by Reza Ena Erlinda, Uky Yudatama, Endah Ratna Arumi

“… Junkyard Auto Park Cafe merupakan salah satu usaha di bidang pariwisata dan kuliner, dalam proses produksi aneka makanan tersebut dibutuhkan bahan baku pangan. …”
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Mezőgazdaság és foglalkoztatás a klímaváltozás szorításában by Bálint Koós, Katalin Kovács, Monika Mária Váradi, Eszter Hamza

“…Míg a klíma változását és a munkaerőhiányt a tudományos kutatások külön vizsgálják, mi arra teszünk kísérletet, hogy összekapcsoljuk őket. …”
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Comparative Effectiveness of Remestemcel-L-rknd versus Ruxolitinib in Pediatric Patients with Steroid-Refractory Acute Graft-Versus-Host Disease using Simulated Treatment Compariso... by Gabriel Tremblay, Dimitrios Tomaras, Eric Strati, Anna Forsythe

“…Outcomes of interest included a 28-day overall response rate (ORR), a 28-day ORR in the grade III-IV aGVHD population, and adverse events (AEs). **Results:** In the full populations, the STC of risk ratios (RRs) found treatment with remestemcel-L-rknd to be associated with a numerical but not statistically significant improvement in the 28-day ORR versus ruxolitinib. …”
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The Impact of Exposure to Indoor Pollutants on Allergy and Lung Inflammation among School Children in Selangor, Malaysia: An Evaluation Using Factor Analysis by Khairul Nizam Mohd Isa, Zailina Hashim, Juliana Jalaludin, Dan Norbäck, Mohammed Abdulrazzaq Jabbar, Jamal Hisham Hashim

“…Abstract A cross-sectional study of 470, 14-year-old students from 8 secondary schools located in sub-urban and urban areas in Hulu Langat district, Selangor, Malaysia was undertaken to determine the impact of atmospheric indoor air pollutants on atopy, asthma, respiratory symptoms and lung inflammation among school children. …”
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Методика визначення програми кута тангажу для виводу космічних апаратів на кругові орбіти by Руслан Кеба, Анатолій Кулабухов

“…Параболічні залежності зміни швидкості, засновані на даних польоту РН Falcon 9 Full Trust, показали, що кутовий рух РН відповідно до запропонованої методології значною мірою збігається з фактичним рухом. …”
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Safety of health workers during the COVID-19 pandemic and beyond: piloting WHO framework in Iran by Jafar Sadegh Tabrizi, Mondher Letaief, Hossein Mashhadi Abdolahi, Ramin Rezapour, Ahmed Alboksmaty, Mostafa Farahbakhsh

“…Most of HWs had completed the full vaccination schedule for Hepatitis B and COVID-19. …”
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Medical complexity in emergency and urgent care settings: a scoping review protocol by Diane Lorenzetti, Tanvir C Turin, Sumedh Bele, Eddy Lang, Doreen Rabi, Naomi Popeski, Marie-Claire Uwamahoro, Conne Lategan, Kate Yakubets, Cassandra Chisholm

“…Two reviewers will independently screen titles and abstracts for inclusion, followed by a screening of the full text of potentially relevant articles. Relevant data will be extracted from these studies. …”
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Smartphone apps for mental health: systematic review of the literature and five recommendations for clinical translation by Aljawharah Almuqrin, Ryan Hammoud, Ilham Terbagou, Stefania Tognin, Andrea Mechelli

“…A risk-of-bias assessment for each study was conducted.Results Out of 4153 non-duplicate articles screened, 31 studies met full-text eligibility criteria. These included 6 studies on treatment apps, 4 on self-monitoring apps and 21 on multipurpose apps for a range of mental health disorders. …”
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Temperature measurements with a temporal scanner: systematic review and meta-analysis by Ruzan Udumyan, Håkan Geijer, Georg Lohse, Ylva Nilsagård

“…Three reviewers selected articles for full-text reading after which a further selection was made. …”
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Childhood occasional hypertension and its association with size at birth and early growth: a population-based retrospective cohort study from China by Shuang Zhang, Leishen Wang, Tao Zhang, Yijuan Qiao, Wei Li, Weiqin Li

“…Methods This study assesses the prevalence of occasional hypertension (OHTN) at 5 ~ 6 years old and evaluates its association with size at birth and BMI at 2 and 5 ~ 6 years old in full-term children. We conducted a population-based cohort study of 12,564 children from 66 kindergartens in Tianjin, China. …”
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Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia by Michael Marks, David Mabey, Ruth Canter, Elizabeth Allen, Charles Opondo, Jennifer Palmer, Iris Mosweu, Jacob Novignon, Sinéad Langan, Maria Zuurmond, Catherine Pitt, Stephen L Walker, Dorothy Yeboah-Manu, Tara Mtuy, Rachel L Pullan, Richard Phillips, Daniel Okyere, Anthony Ablordey, Samantha Owen, Portia Boakye Okyere, Kidist Bobosha, Katherine Halliday, Steve Walker, Galana Mamo Ayana, Rachel Pullan, Mirgissa Kaba, Tara B Mtuy, Yaw Amoako, Adwoa Asante-Poku, Abigail Agbanyo, Eric Koka, Joseph Timothy, Yohannes Hailemichael, Abebaw Yeshambel Alemu, Teklu Cherkose, Getachew Kebebew, Fikregabrail Aberra Kassa, Tedros Nigusse, Kibur Engedawork, Zenebu Begna, Abay Waday, Saba Lambert, Katherine Elizabeth Halliday, Endalamaw Gadisa, Vanessa Yardley, Collins Ahorlu, Anita Achiaa Gyekye, Emmanuel Afreh, Esther Amon, Abraham Kwabena Anang, Ruth Dede Tuwor, Giulia D’Odorico, Kibur Engidawork, Mehari Getaneh, Bernadette Morkporkpor, Emmanuel Narh, Dorcas Opai-Tetteh, Yohannes Michael, Amel Mohammed, Fewzia Shikur Mohammed, Shimelis Doni Nigusse, Maja Niksic, Edmond Okloo, Michael Oppong, Lucy Owusu, Ishaque Siam, Ingrid Sobel, Feleke Tilahum, Joseph Tuffour, Abay Woday, Abebaw Yeshambel, Adelaide Forkuo- Boadu, Derrick Kontoh, Jojo Cobbinah

“…To inform these strategies, we aimed to understand the social, economic and health system context of skin NTD care in Kalu woreda, Amhara region, Ethiopia, where cutaneous leishmaniasis (CL) and leprosy are endemic.Methods Between October 2020 and May 2022, we surveyed and reviewed records of 41 primary healthcare facilities and explored common disease experiences in focus group discussions (n=40) and interviews with people affected by leprosy (n=37) and CL (n=33), health workers (n=23), kebele authorities and opinion leaders (n=33) and traditional healers (n=7). …”
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A ribodepletion and tagging protocol to multiplex samples for RNA-seq based virus detection: application to the cassava virome by Daniel H. Otron, Justin S. Pita, Murielle Hoareau, Fidèle Tiendrébéogo, Jean-Michel Lett, Pierre Lefeuvre

“…After confirming that the protocol was suitable for ribodepletion, we demonstrated it was possible to detect RNA and DNA viruses via identification of near full-size genomes. Additional phylogenetic analyses confirmed the presence of begomoviruses and ipomoviruses responsible for CMD and CBSD, respectively. …”
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Congenital vitamin D deficiency: presenting with feeding difficulty in early infancy: a case report by Mesfin Wubishet, Tesfa G. Meskel, Kibret Enyew

“…Case presentation We present the case of a 50-day-old Ethiopian full-term infant, born to a Muslim Ethiopian mother, who experienced feeding difficulties, frequent brief episodes of apnea, and cyanosis since birth. …”
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People’s knowledge, attitudes, and conflicts with carnivores in central hills, Sri Lanka by Ashan Thudugala, Hem Bahadur Katuwal, Nalindra Laxman, Vishwa Dushmantha, Ravindi Menikrama, Harsha Dissanayake, Chameera Dilshan, Ru-Chuan He, Rui-Chang Quan

“…Respondents demonstrated a strong understanding of environmental laws, including forest and wildlife regulations and the penalties associated with killing species. Forty-one percent of the respondents expressed a positive attitude toward one of the carnivores, particularly leopards and other cat species, while 74 % particularly showed a negative attitude toward the civet species. …”
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Host factor PLAC8 is required for pancreas infection by SARS-CoV-2 by Lesly Ibargüen-González, Sandra Heller, Darío López-García, Hanna Dietenberger, Thomas FE Barth, Patricia Gallego, Israel Fernández-Cadenas, Sayoa Alzate-Piñol, Catalina Crespí, Julieth A. Mena-Guerrero, Eugenia Cisneros-Barroso, Alejandro P. Ugalde, Gabriel Bretones, Charlotte Steenblock, Alexander Kleger, Marta L. DeDiego, Carles Barceló

“…Functional experiments demonstrate the requirement of PLAC8 in SARS-CoV-2 pancreatic productive infection by pseudovirus and full SARS-CoV-2 infectious virus inoculum from Wuhan-1 and BA.1 strains. …”
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A Cost-effectiveness Analysis of Brentuximab Vedotin in Relapsed or Refractory Systemic Anaplastic Large Cell Lymphoma by Margaret Hux, Denise Zou, Esprit Ma, Peter Sajosi, Andreas Engstrom, Ross Selby, Eugene Benson, Andrew Briggs, Vijayveer Bonthapally

“…**Conclusion:** Compared to conventional chemotherapy, and considering the full survival period, brentuximab vedotin may provide a valuable treatment choice for patients with R/R sALCL, a population with limited therapeutic options.…”
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Evaluation of three-dose fosfomycin tromethamine in the treatment of patients with urinary tract infections: an uncontrolled, open-label, multicentre study by Shan Chen, Yong Yang, Bo Yang, Ming Chen, Kai Zhang, Yi Wang, Lu-Dong Qiao, Bo Zheng, Hong-Feng Guo, Yuan-Jie Niu, Ben-Kang Shi, Wei-Min Yang, Xiao-Kun Zhao, Xiao-Feng Gao

“…Clinical symptoms, physical signs, urinalysis, liver and kidney function, patient records and evaluation of adverse events (AEs) and serious AEs up to day 15 were evaluated for analysis of safety.Results 361 patients were included in the full analysis set, 356 in the safety analysis set and 335 in the per-protocol set (PPS). …”
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Target Detection Using Fused Unidentical Photonics-Based LFM Sub-Band Radar Signals With an Adaptive Feed Forward Network Equalizer by Bikash Nakarmi, S. M. Rezwanul Islam, Hum Nath Parajuli, Ikechi Augustine Ukaegbu, Aigerim Ashimbayeva, Carlo Molardi, T. D. Subash, Xiangchuan Wang, Shilong Pan

“…The FFNE achieves significant improvement over 10 dB in PSL and resolves previously unresolvable distances, with maximum range resolutions of 1.8 cm, 2.2 cm, and 2 cm, closely matching theoretical values for full-band LFM signals with bandwidth of 9.06 GHz, 7.31 GHz, and 9 GHz, respectively. …”
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Irritable Bowel Syndrome: What Are the Reasons for Dissatisfaction with the Treatment of Patients and Doctors? (Based on the Experience of Medical Institutions of the Northwestern... by A. Yu. Baranovsky, T. V. Reshetova, I. S. Sakeyan

“…The treatment complex for IBS patients can be considered optimal if, in addition to symptomatic medications, appropriate psychotropic medications are necessarily included in it basing on diagnostic assessment of the psychoemotional status of a particular patient, as well as the appointment of individually selected non-medicinal methods of psychological correction in accordance with psychosomatic symptoms. Full-time cycles on psychodiagnostics and psychotherapy should be included in the educational programs of advanced training of doctors working with IBS patients.…”
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