β2 integrin regulates neutrophil trans endothelial migration following traumatic brain injury by Lei Li, Ruilong Peng, Cong Wang, Xin Chen, Dilmurat Gheyret, Siyu Guan, Bo Chen, Yafan Liu, Xilei Liu, Yiyao Cao, Cha Han, Jianhua Xiong, Fanjian Li, Taoyuan Lu, Haoran Jia, Kaiji Li, Jinchao Wang, Xu Zhang, Jianye Xu, Yajuan Wang, Xin Xu, Tuo Li, Jianning Zhang, Shu Zhang

“…The precise molecular controls that dictate the inflammatory behavior of neutrophils post-TBI, however, remain largely elusive. Our comprehensive analysis of the molecular landscape surrounding the trauma in TBI mice has revealed a significant alteration in the abundance of β2 integrin (ITGB2), predominantly expressed by neutrophils and closely associated with immune responses. …”
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Evaluating Sampling Uncertainty in the Quantitative 1H Nuclear Magnetic Resonance Analysis of Lignin by Shrikant Shivaji Pawade, Lauri Toom, Koit Herodes, Ivo Leito

“…In recent years, lignin analysis utilizing quantitative nuclear magnetic resonance (qNMR) has attracted considerable interest and has been the subject of numerous studies. However, evaluating the measurement uncertainty of qNMR results of lignin remains a challenge. …”
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FARMERS -HERDERS CONFLICTS IN NIGERIA AND INTERNAL DISPLACEMENT IN NIGERIA by FRANCESCA ESSIEN

“…Findings of the study showed that, although the main reason of the conflict is the scarcity of land resources, several other factors such as population pressure, inefficient state mechanisms, climate change, increasing proliferation of arms etc have fueled the conflict in recent years. However, the most immediate trigger to the surge in farmer-herder violence in the country, is the activities of the violent militant groups. …”
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An investigation of hydraulic fracturing initiation and location of hydraulic fracture in preforated oil shale formations by Lianghao Zhai, Yang Xun, Huanan Liu, Bo Qi, Jinghua Wu, Yafei Wang, Chen Chen

“…Abstract Horizontal well fracturing technology enables the commercial production of low-permeability reservoirs, with perforation fracturing technology serving as a critical component of multistage fracturing for horizontal wells. However, the presence of the horizontal wellbore and the perforation borehole significantly complicates the distribution of the local stress field. …”
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Overcoming single-technology limitations in digital heritage preservation: A study of the LiPhoScan 3D reconstruction model by Yao Wang, Wei Bi, Xiaodong Liu, Yan Wang

“…With the increasing demand for the digital preservation of cultural heritage, high-precision 3D reconstruction of museum artifacts has become an important research direction. However, single technology approaches face limitations in practical applications, such as insufficient capture of geometric details, poor texture fidelity, and suboptimal geometric accuracy. …”
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A Comparative Study of Hybrid Adaptive Neuro-Fuzzy Inference Systems to Predict the Unconfined Compressive Strength of Rocks by Annabelle Graham, Emma Scott

“…The precise estimation of Unconfined Compressive Strength (UCS) in rock samples is paramount for the effective planning and execution of mining and civil engineering projects. However, the inherent variability and discontinuity within rock masses present challenges in obtaining accurate physico-mechanical data. …”
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Comparison of Vitamin-D binding protein levels in gingival crevicular fluid of pre- and postmenopausal women with and without chronic periodontitis: A clinico-biochemical study by Kaviya Balasubramaniyam, Sankar Lakshmi Sree, Kavitha Jayavel, V. Krishnan, Rajasekar Sundaram

“…Vitamin-D Binding Protein (DBP) is a multifunctional protein that acts as an acute phase reactant and plays a key role in bone metabolism. Aim: The aim of this study was to assess and compare DBP levels in Gingival Crevicular Fluid (GCF) of pre- and postmenopausal women with and without chronic periodontitis. …”
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Early detection of myocarditis caused by immune checkpoint inhibitor therapy with nivolumab and ipilimumab for advanced recurrent renal cell carcinoma by Maki Todo, Yodo Gatate, Shintaro Nakano, Go Kaneko, Masayuki Hagiwara, Takayuki Takahashi, Yuta Umezawa, Genji Ueda, Shiho Ishikawa, Yoshinori Makino, Masafumi Oyama, Suguru Shirotake

“…Abstract Combination therapy with nivolumab and ipilimumab for advanced renal cell carcinoma (RCC) may cause immune-related myocarditis; however, its incidence in this cancer type and regimen remains unknown. …”
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Nose-clip use in semi-free ranging pigs reduces rooting without disrupting affiliative behaviour or causing prolonged stress by E. Collarini, O. Dal Monte, M. Traversa, E. Mecarelli, C. Medana, S. Visentin, G. Cordoni, I. Norscia

“…Domestic pigs (Sus scrofa) raised under natural conditions can show their complete behavioural repertoire. However, rooting behaviour can have a great impact on the environment. …”
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Multi-organ frailty is enhanced by periodontitis-induced inflammaging by Yoshitaka Kase, Satoru Morikawa, Yuji Okano, Tatsuya Hosoi, Takazumi Yasui, Yoko Taki-Miyashita, Mitsutaka Yakabe, Maraku Goto, Kazuyuki Ishihara, Sumito Ogawa, Taneaki Nakagawa, Hideyuki Okano

“…Abstract Background The incidence of periodontitis is high in older individuals. However, its impact on multi-organ frailty remains unclear. …”
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Oral lactoferrin as a treatment of pediatrics’ anemia resulted from chronic kidney diseases: a randomized controlled trial by Sahar Kamal Hegazy, Mai Salah El-Din Koura, Mohamed Shokry Elharoun

“…Both treatments are effective in treating CKD-induced anemia in pediatrics; however, oral lactoferrin demonstrated superior efficacy as there was a significant change within that group in levels of Hb, RBCs, MCH, iron, RDW-SD, MCHC, IL-6, and GDF-15 before and after treatment. …”
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TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep. by Li-Xia Qiu, Qian Yu, Hua-Qian Zhou, Wen-Hua Fan, Jing-Jing Zheng, Yong-Lin Yang, Wen-Zhe Zhang, Xin Cao, Hua Yang

“…The development of secondary hair follicles influences the quality of sheep wool. However, the mechanism by which proteins mediate the fetal development of secondary hair follicles remains unknown. …”
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Protecting Florida Panthers by Protecting Domestic Animals: Building a "Panther-Proof" Pen by Phillip D. Rodgers, Elizabeth F. Pienaar, Mark Lotz, Darrell Land

“…For the most part, the role of panthers in the natural environment benefits people (they prey on burgeoning populations of white-tailed deer, raccoons, opossums, and feral hogs). …”
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RTEL1 is upregulated in gastric cancer and promotes tumor growth by Chunyu Yang, Suzeng Wang, Ge Gao, Peiwen Xu, Mengyuan Qian, Yuan Yin, Surui Yao, Zhaohui Huang, Zehua Bian

“…Regulator of Telomerase Length 1 (RTEL1) has been found to maintain telomere stability through its helicase activity, facilitating telomere reconstruction and repair. However, the precise role of RTEL1 in human cancers, particularly in GC, is not yet fully understood. …”
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Unignorable Emissions and Potential Health Effects of Unregulated Pollutants from Nonroad Engines Using Greener Fuels — A Review by Lulu Duan, Yu-Lun Hsieh, Sheng-Lun Lin, Wan Nurdiyana Wan Mansor, Muhammad Isyhraff Azhan Bin Mansor, Hyojun Lee, Chien-Er Huang, How-Ran Chao, Mengjie Song, Minseop Song

“…Countries worldwide have implemented stringent emission regulations targeting pollutants like CO, HC, NOx, and PM. However, these machines also emit unregulated pollutants such as PAHs, VOCs, POPs, and metals, which severely impact human health and the atmosphere. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…Existing therapies primarily rely on personalized pharmacotherapy and lifestyle modifications. However, these treatments may often lead to adverse effects, and most medications prescribed for PCOS are used off-label and have not secured approval from the U.S. …”
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Mexiletine dosing and tolerability in refractory chronic migraine: Insights from post-lidocaine infusion treatment by Lucia Liao, Hsiangkuo Yuan, Dylan Selbst, Emily Casaletto, Jiangang Liao, Clinton G. Lauritsen

“…Background Mexiletine is used as a preventive medication for refractory chronic migraine (rCM) and to prolong migraine improvement following intravenous lidocaine infusion. However, published evidence supporting its use in migraine remains limited. …”
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Evidence based use of antibiotics in epidemic keratoconjunctivitis to prevent development of microbial resistance by Shalini Kumari, Imsensenba Longkumer, Mamta Sharma, Shashank Tripathi

“…Aim: It was thought that resistance acquired during treatment of systemic diseases can lead to resistant bacteria in eye infections. However, evidences are showing emergence of bacterial resistance owing to prior topical antibiotic usage. …”
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The Challenge of Implementing Smoking Prevention Measures in Malaysia: An Analysis from a Hadith Perspective by Rahim Kamarul Zaman, Ahmad Sanusi Azmi, Razin Mohamed Rosli, Alia Abdul Rashid

“…In line with WHO's goals, the Malaysian Ministry of Health proposed the Generational Endgame (GEG) policy to curb smoking and nicotine addiction among the younger generation. However, in 2023, the Malaysian government removed nicotine from the list of controlled substances, contradicting the efforts to control smoking and nicotine as per the WHO's aspirations. …”
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Open Surgery for Patellar Tendon Rupture and Tibial Tuberosity Avulsion Fracture in Pre-Existing Osgood Schlatter Lesion: A Case Report by Shianita Limena, Anak Agung Ngurah Ronny Kesuma, I Komang Mahendra Laksana

“…The various surgical treatment methods have been reported; however, surgical modification technique is performed accordingly due to the complicated case presentation. …”
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