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8521
Identification of Houge type of X-linked syndromic mental retardation caused by CNKSR2 truncated variants
Published 2025-02-01“…MRXSHG is a serious disorder with CNKSR2 variant and at least 34 variants have been identified in MRXSHG patients. However, the genotype-phenotype correlation and variants characteristics of CNKSR2 need further investigation and improvement. …”
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8522
Vitrification affects the post-implantation development of mouse embryos by inducing DNA damage and epigenetic modifications
Published 2025-02-01“…Blastocyst and implantation frequencies were not significantly affected by vitrification. However, vitrification significantly reduced blastocyst cell number and the live pup frequency. …”
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8523
Improvement of the dissolution of the antineoplastic drug regorafenib through impregnation into pullulan polysaccharide using supercritical fluid technology: Optimization of the pr...
Published 2025-03-01“…Regorafenib is administered orally for the treatment of metastatic colorectal cancer. However, its limited water solubility hinders its clinical efficacy. …”
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8524
Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk
Published 2025-02-01“…For example, S. agalactiae growth was enhanced with 1 % oleic acid but suppressed at 0.01 %; however, the effects were directionally opposite for linoleic acid, i.e., suppressed at 1 % but enhanced at 0.01 %. …”
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8525
The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis
Published 2025-02-01“…The 5-methylcytosine (m5C) RNA methyltransferase NSUN2 is involved in cell proliferation and metastasis and is upregulated in a variety of cancers. However, the biological function and regulatory mechanism of NSUN2-mediated m5C modification have not been well studied in HCC. …”
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8526
Dimorphos’s Material Properties and Estimates of Crater Size from the DART Impact
Published 2025-01-01“…Images from DART’s DRACO camera revealed Dimorphos to be an oblate spheroid covered in boulders of varying sizes and shapes. Very little was known about Dimorphos prior to DART’s impact, including its shape, structure, and material properties. …”
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8527
Correlation of Anti-Müllerian Hormone with Polycystic Ovarian Disease and its Relation with Age
Published 2019-08-01“…Sample size estimation was performed by "GPower 3.1" and "IBM SPSS Statistics version 25" was used for analysis of data. …”
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8528
The Impact of Green Human Resource Management on IT Employees’ Environmentally Eco-friendly Performance and Behavior: The Mediating Role of Organizational Commitment
Published 2025-02-01“…This study also investigated the mediating role of organizational commitment on the nexus between GHRM and employees’ environmentally friendly and eco-friendly behavior. …”
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8529
Fecal bacteria transplantation replicates aerobic exercise to reshape the gut microbiota in mice to inhibit high-fat diet-induced atherosclerosis.
Published 2025-01-01“…Aerobic exercise exerts a significant impact on the gut microbiota imbalance and atherosclerosis induced by a high-fat diet. However, whether fecal microbiota transplantation, based on aerobic exercise, can improve atherosclerosis progression remains unexplored. …”
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8530
Prevalence and socioeconomic determinants of awareness and visitation of community clinic among ever married women: evidence from Bangladesh Demographic and Health Survey, 2017–201...
Published 2023-02-01“…Moreover, male household heads and exposure to media were significantly positively related to visitation to CCs.Conclusion The study result highlights that more than half of the women were aware of CCs however, the CCs’ visit rates were comparatively low. …”
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8531
RELATIONSHIP OF ACL INJURY WITH POSTERIOR TIBIAL SLOPE, INTERCONDYLAR NOTCH WIDTH RATIO, AGE, AND SEX
Published 2019-12-01“…Posterior tibial slope (PTS) has been proposed as a potential risk factor for ACL injury; however, studies that examined this relationship have provided inconclusive and sometimes contradictory results. …”
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8532
Insights into the nuclear-organelle DNA integration in Cicuta virosa (Apiaceae) provided by complete plastid and mitochondrial genomes
Published 2025-02-01“…Abstract Background Gene transfer between the organelles and the nucleus plays a central role in shaping plant genome evolution. The identification and analysis of nuclear DNA of plastid (NUPTs) and mitochondrial (NUMTs) origins are important for exploring the extent of intracellular DNA transfer in genomes. …”
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8533
Misuse of prescription medicines is as prevalent as the use of recreational drugs and novel psychoactive substances in Singapore: an unrecognised public health issue?
Published 2022-10-01“…Introduction: Misuse of prescription medicines and the harms associated with such use are growing threats across the world. There is currently, however, limited data on the extent of prescription medicine misuse in Singapore and whether this is a current threat in the country. …”
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8534
Ex vivo delivery of recombinant IL-10 to human donor lungs
Published 2025-02-01“…Background: The immunoregulatory cytokine interleukin-10 (IL-10) has been shown to be a promising therapy for donor lung injuries before transplantation. However, the very short half-life of IL-10 in vivo (∼2 hours) has necessitated the use of gene therapy in almost all animal models of lung transplantation. …”
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8535
DYNAMIC INTERACTIONS AMONG EXCHANGE RATE, PERFORMANCE OF MANUFACTURING SECTOR AND INFLATION IN NIGERIA: AN ARDL APPROACH
Published 2023-11-01“…Secondary and annual time series data that covered 1981 to 2018 are sourced from World Development Indicator (WDI) published by World Bank Organization. …”
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8536
Influences of a Quasi-stationary Front on Particulate Matter in the Low-latitude Plateau Region in China
Published 2020-09-01“…When the KMQSF moved westward from the center of the LoLaP, the easterly wind transported PM to the western part of the region, which led to an increase in the mean daily PM10 and PM2.5 concentrations in Kunming, a capital city in that area; simultaneously, however, the PM10 and PM2.5 levels remained high in Guiyang, a capital city in the eastern part of the LoLaP. …”
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8537
Prior Information Shapes Perceptual Confidence
Published 2025-01-01“…Decisional confidence refers to the subjective evaluation of the accuracy of a decision based on sensory information. …”
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8538
GIS-based multi-criteria decision making for identifying rainwater harvesting sites
Published 2025-02-01“…The nine primary criteria considered were rainfall, elevation, slope, stream order, soil texture, land use, groundwater depth, distance from the lake, and runoff depth. …”
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8539
Serialised Translations in the Estonian Newspapers in the Beginning of the 20th Century (1900‒1940)
Published 2024-07-01“…The study uses the years 1906–1911 and 1928–1933 as a sample for content analysis of the feuilleton sections of the two newspapers in order to examine the changes in source literatures and the category of literature. …”
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8540
Tracking of The Most Significant Laboratory Parameters For The Identification of Covid-19: An Overview on The Different Blood Tests
Published 2020-06-01“…An outbreak of 2019 novel coronavirus disease (COVID-19) began in China during December 2019 which unexpectedly spread to other countries and caused high mortality all over the world. COVID-19 disease primarily manifests as a respiratory tract infection. …”
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