Investigation of Association with First-Trimester Free Human Chorionic Gonadotropin-ß, Pregnancy - Associated Plasma Protein-A, and Adverse Pregnancy Outcomes by Gokhan Gonen, Yasam Kemal Akpak, Murat Muhcu

“… OBJECTIVES: This study aimed to investigate the association between first-trimester screening maternal serum markers (free human chorionic gonadotropin-beta (β-hCG), pregnancy-associated plasma protein-A, and adverse pregnancy outcomes (gestational hypertension, preeclampsia, preterm delivery, intrauterine growth restriction, oligohydramnios, intrauterine ex-fetus, abruptio placentae, and gestational diabetes mellitus). …”
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Comparison of Modified Biophysical Profile with Doppler Ultrasonographic Analysis in Determining Fetal well Being in the Third Trimester by Kadir Bakay, Ahmet Varolan, Ali Yazgan, Atif Akyol, İnci Davas

“…In conclusion, in order to effectively predict acute fetal distress and to maintain a reliable screening method, combined use of these tests, namely modified biophysical profile and umbilical artery Doppler analysis, has proven to be the most valuable and effective method as shown in our study. …”
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Risk prediction models for stress urinary incontinence after pelvic organ prolapse (POP) surgery: a systematic review and meta-analysis by Bi Jun Yu, Hao Chong He, Li Wang, Han Mei Shao, Ying Min Liu, Xiao Ying Yan, Jian Liu

“…Methods Relevant literature in PubMed, Embase, Web of Science, Cochrane Library, OVID, China National Knowledge Infrastructure(CNKI), Wan Fang Database, VIP database and Chinese Biomedical Literature Service System (SinoMed) were search from inception to 1 March 2024. Literature screening and data extraction were performed independently by two researchers. …”
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Inhibition of TFF3 synergizes with c-MET inhibitors to decrease the CSC-like phenotype and metastatic burden in ER+HER2+ mammary carcinoma by Chuyu He, Xuejuan Wang, Yi-Shiou Chiou, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie

“…Furthermore, a high-throughput combinatorial anti-cancer compound library screening revealed that AMPC preferentially synergized with receptor tyrosine kinase c-MET inhibitors (c-METis) to reduce cell survival and the CSC-like phenotype. …”
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Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial... by Claus Thorn Ekstrøm, Patrick MacDonald Fisher, Gitte Moos Knudsen, Dea Siggaard Stenbæk, Anders Fink-Jensen, Mathias Ebbesen Jensen, Tobias Søgaard Juul

“…All patients will be provided oral and written information about the trial before screening. The study results will be disseminated by peer-review publications and conference presentations.Trial registration number EudraCT 2020-000829-55 and NCT05416229.…”
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Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

“…The therapeutic effect of Baji capsule was evaluated by high-resolution micro-computed tomography (Micro-CT) and tissue section staining, serum inflammatory factor levels were assessed by ELISA, serum oxidative stress-related marker levels were determined by kits, and finally the mechanism was explored by network pharmacology and then verified by immunohistochemistry.Results: Micro-CT results showed that Baji capsule attenuated LPS-induced inflammatory bone loss.Baji capsule also reduced serum inflammatory factor levels and oxygen free radical production. Target screening by network pharmacology yielded a total of 236 active ingredients of Baji capsule, as well as 278 common targets after taking the intersection of Baji capsule active ingredient targets and osteoporosis disease-related targets.Conclusion: Baji capsule can treat osteoporosis by reducing inflammation and oxidative stress. …”
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Balloon dilation for the treatment of male urethral strictures: a systematic review and meta-analysis by Tianyu Cai, Xiaoyu Li, Jian Lin, Chunru Xu, Xing Ji, Zhenpeng Zhu, Zhenke Guo

“…The aim of this study was to review and discuss the safety, efficacy and factors influencing the clinical application of balloon dilation for the treatment of male urethral strictures.Design Systematic review and meta-analysis.Data sources Embase, Medline, Web of Science, Cochrane Library and Scopus were searched for publications published before 17 July 2022.Study selection Two independent researchers screened and assessed the results, and all clinical studies on balloon dilation for the treatment of urethral strictures in men were included.Data extraction and synthesis The success rate, rate of adverse events, International Prostate Symptom Scores, maximum uroflow (Qmax) and postvoid residual urine volume were the main outcomes. …”
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Need to clamp indwelling urinary catheters before removal after different durations: a systematic review and meta-analysis by Xiaoyan Fan, Sumin Ma, Jiayi Gu

“…Objective This meta-analysis aimed to evaluate the effect of bladder training by clamping on bladder urethral function in patients with indwelling urinary catheters used for different durations.Design Systematic review and meta-analysis.Data sources The UpToDate, Cochrane Library, OVID, PubMed, China National Knowledge Infrastructure, CINAHL and Embase were screened from 1 January 2000 to 28 February 2022.Eligibility criteria for selecting studies Randomised controlled trials (RCTs) or quasi-experimental designs comparing the efficacy of bladder training in patients with an indwelling urinary catheter by clamping or free drainage before urinary catheter removal were published in English or Chinese.Data extraction and synthesis Two reviewers independently extracted the data and assessed the quality of studies. …”
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A Study on Diagnostic Accuracy of Dipsi Method Over Traditional Oral Glucose Tolerance Test Among Antenatal Women by Vijayadevi Shanmugam, Dharani Sudha Gopalraj, Shruthi Nanjudappan, Rajeswari Ravindran

“…Various diagnostic criteria and methods, such as the Diabetes in Pregnancy Study Group of India (DIPSI) criteria, IADPSG (International Association of the Diabetes and Pregnancy Study Groups) have been debated for GDM screening. This study is aimed to compare the DIPSI and IADSP criteria which is widely used in India with the World Health Organization (WHO) criteria and assess their diagnostic accuracy. …”
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Performance of artificial intelligence on cervical vertebral maturation assessment: a systematic review and meta-analysis by Termeh Sarrafan Sadeghi, Seyed AmirHossein Ourang, Fatemeh Sohrabniya, Soroush Sadr, Parnian Shobeiri, Saeed Reza Motamedian

“…Results A total of 1606 studies were screened of which 25 studies were included. The performance of the models was acceptable. …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…In PROPEL, EQ-5D-5L values were assessed at screening and at weeks 12, 26, 38, and 52. EQ-5D-5L utility values were mapped to EQ-5D-3L values using the van Hout algorithm as recommended by the EuroQoL and the National Institute of Health and Care Excellence position statement at time of analysis. …”
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Differentiated approach at the choice of chronic hepatitis C antiviral therapy mode (real clinical practice experience) by I. Yu. Pirogova, N. B. Kovaleva, E. P. Patlusov, E. S. Radchenko

“…Results of the present study demonstrate that screening for treatment candidates allows to achieve high efficacy and favorable safety profile of double treatment mode (cPEG-IFNα2b and ribavirin).…”
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Kalar1 and Kalar2, Newly Released Wheat Varieties for Cultivation under Rain-fed Conditions by Star Ali Awtaq, Ali Shamsullah Azeez, Yadgar Ali Mahmood, Narmeen Rashid Abdulkareem, Khalil Musa Jamal

“…In the selection phase, 50 lines of Facultative and Winter Wheat Observation Nurseries (16th FAWWON-IR) were screened, and three superior lines (SL1; CH75479/SARDARI-HD74, SL2; CATBERD/CNO79*2/HEF1, and SL3; ID800994.W/VEE/5/CA8055/4/ROMTAST/BON/3/DIBO//SU) to the best local check (Aras) for grain yield, thousand grain weight, anthesis date and plant height were selected for testing in three field trials of comparison phase. …”
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Exploring the efficacy of psychotherapies for depression: a multiverse meta-analysis by Eirini Karyotaki, Pim Cuijpers, Constantin Yves Plessen, Clara Miguel, Marketa Ciharova

“…This study was preregistered (https://doi.org/10.1136/bmjopen-2021-050197).Findings A total of 21 563 records were screened, and 3584 full texts were retrieved; 415 studies met our inclusion criteria containing 1206 effect sizes and 71 454 participants. …”
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Comparative efficacy of clopidogrel-aspirin combination therapy versus aspirin monotherapy in preventing recurrent events in transient ischemic attack and minor stroke: a systemati... by Ahmad Mujtaba Bhutto, Rana Ali Raza, Mohammad Bilal Abbasi, Iman Jauhar, Naeemullah Arbani, Muhammad Mubashir, Abdul Raheem, Taha Basit Ameen, Syed Muhammad Sinaan Ali

“…Results From 2344 articles screened, 33 studies involving 15,376 participants were included. …”
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Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia by Carlos Mario Cortes Bahamon, Jenny Rodríguez Ángel, Jennifer Katherine Ballesteros Tapias, Diego Andrés Chavarro-Carvajal, Oscar Mauricio Muñoz

“…Malnutrition was documented in 22.4%, dependency for basic activities (Barthel ⩽ 95) in 75.9%, and positive screening for frailty (FRAIL ⩾ 3) in 55.3%. Mortality was 5.67%. …”
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Impact of fetal sex on neonatal outcomes in women with gestational diabetes mellitus: a systematic review and meta-analysis by Mahsa Maghalian, Zohreh Alizadeh-Dibazari, Mojgan Mirghafourvand

“…Results From 702 studies screened, twelve observational studies were included in the analysis. …”
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Evaluation of pathology resources for cervical cancer detection between 2018 and 2022: a retrospective study at Moi Teaching and Referral Hospital, Western Kenya by Nelson Anangwe, Jon Steimgrimson, Susan Cu-Uvin

“…Turnaround time (TAT) was assessed against the UK’s National Health Service Cervical Screening Program guidelines. Results The number of histopathology laboratory personnel at MTRH increased from 2018 to 2022, during which the facility included two pathologists, one records person, and one office administrator. …”
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Genome-based analysis of the genetic pattern of black sheep in Qira sheep by Wen Zhou, Xiaopeng Li, Xuechen Zhang, Lijun Zhu, Yuwei Peng, Cheng-long Zhang, Zhipeng Han, Ruizhi Yang, Xinyu Bai, Quanfeng Wang, Yuejun Zhao, Shudong Liu

“…The region of exon 1 of the TYRP1 gene was further screened, amplified and sequenced through the DNA of the Qira sheep and associated with goodness-of-fit using the chi-square test. …”
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Effects of manual osteopathic interventions on psychometric and psychophysiological indicators of anxiety, depression and stress in adults: a systematic review and meta-analysis of... by Darren J Edwards, Jerry Draper-Rodi, Danny Miller, Josh Hope-Bell, Andrew MacMillan, Tom C Gordon

“…Objectives To evaluate whether osteopathic and related manual interventions improve adult mental health (depression, anxiety, stress) and psychophysiological measures (eg, heart rate variability, skin conductance).Design Systematic review and meta-analysis of randomised controlled trials (RCTs).Data sources PubMed, MEDLINE (Ovid), Scopus, Cochrane, and AMED, searched through September 2024.Eligibility criteria English-language RCTs with ≥30 participants investigating osteopathic or related manual therapies (eg, myofascial release, high-velocity low-amplitude thrusts) delivered by qualified practitioners, compared with no treatment or sham, and reporting immediate postintervention mental health or psychophysiological outcomes.Data extraction and synthesis Full-text screening, risk-of-bias assessment and data extraction were conducted independently by multiple reviewers using a standardised Joanna Briggs Institute (JBI) Extraction Form. …”
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