Genetic differentiation and historical dynamics of the endemic species Rheum pumilum on the Qinghai-Tibetan Plateau inferred from phylogeography implications by Shuliang Liu, Jianxin Gao, Bo Xiao, Wenjie Guo, Qiushi Yu, Ailan Wang, Weiwei Li

“…Abstract Background Rheum pumilum, an endemic species on the Qinghai-Tibetan Plateau (QTP), serves as an ideal material for investigating the phylogeography of alpine plants. …”
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Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax by Caroline A. Coughlin, Dhanvantri Chahar, Marianna Lekakis, Abdessamad A. Youssfi, Lingxiao Li, Evan Roberts, Natalia Campos Gallego, Claude-Henry Volmar, Ola Landgren, Shaun Brothers, Anthony J. Griswold, Catalina Amador, Daniel Bilbao, Francesco Maura, Jonathan H. Schatz

“…Though potentially curable with frontline combination chemoimmunotherapy, DLBCL carries persistently poor prognosis for those with relapsed or refractory (rel/ref) disease, despite recent advances in immunotherapy. Here, we build on recent findings implicating gain-of-function mutations in the BCL10 signaling protein as drivers of resistance to Bruton’s tyrosine kinase (BTK) inhibitors. …”
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A sarcopenia prediction model based on the calf maximum muscle circumference measured by ultrasound by An Wei, Yan Zou, Zhen-Hua Tang, Feng Guo, Yan Zhou

“…The sensitivity, specificity, and AUC of the model were 0.884 (0.807–0.962), 0.837 (0.762–0.911), and 0.927 (0.890–0.963), respectively. …”
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Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer: a prospective cohort study by Zeyin Hu, Mengna Luo, Ruoying He, Zhenming Wu, Yuying Fan, Jia Li

“…Data on patient-, laboratory- and catheter-related risk factors were collected on the day of catheterization. Patients were investigated for PICC-RVT by Doppler sonography in the presence of PICC-RVT signs and symptoms. …”
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Visual, clinical and quality of life outcomes of a new multifocal IOL with optimized diffractive grating: a non-randomized clinical trial by João Marcelo de Almeida Gusmão Lyra, Mariana Silva Gois de Almeida, Lucila de Albuquerque Barbosa Lira, Laís Oliveira dos Santos, Mateus Lins dos Santos, Jorge Artur Peçanha de Miranda Coelho

“…Additionally, intraoperative and postoperative complications were documented. Visual acuity assessments were performed under photopic conditions, with a range of defocus from + 1.5 D to -3.0 D. …”
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Empowering access: unveiling an overall composite spatial accessibility index to healthcare services in Southeastern Iran by Ahmad Raeesi, Soheil Hashtarkhani, Mahmood Tara, Narjes Sargolzaei, Behzad Kiani

“…Spatial accessibility for general practitioners, nursing, dentistry, midwifery, pharmacy, medical laboratory, nutrition, public health, radiology, psychology, environmental health, rural health workers, inpatient hospital beds, and five medical specialty services were calculated. Spatial accessibility scores were normalized from 0 to 1 (no access = 0, low = 0.01 to 0.33, moderate = 0.331 to 0.66, high = 0.661 to 1) and aggregated into overall indices of primary, secondary, and overall healthcare accessibility for each district. …”
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Diagnostic efficacy and necessity of 18F-FDG PET/CT in fever of unknown origin: insights from a retrospective cohort study by Xiaoman Yu, Shuang Wang, Na Du, Hongguang Zhao, Haiying Chen

“…Additionally, univariate and multivariate logistic regression analyses were performed to evaluate the predictive value of relevant laboratory indices on the true-positive results of 18F-FDG PET/CT. …”
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Accounting for racial bias and social determinants of health in a model of hypertension control by Yang Hu, Nicholas Cordella, Rebecca G. Mishuris, Ioannis Ch. Paschalidis

“…Methods In this retrospective cohort study, records from 1/1/2012 to 1/1/2020 at the Boston Medical Center were used. Patients with either a hypertension diagnosis or related records (≥ 130 mmHg systolic or ≥ 90 mmHg diastolic, n = 164,041) were selected. …”
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A Study on Diagnostic Accuracy of Dipsi Method Over Traditional Oral Glucose Tolerance Test Among Antenatal Women by Vijayadevi Shanmugam, Dharani Sudha Gopalraj, Shruthi Nanjudappan, Rajeswari Ravindran

“…The blood sugar values were classified, and diagnostic accuracy was measured using sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). …”
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Advancing Alzheimer’s disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study by Yanfei Chen, Bing Wang, Yankai Shi, Wenhao Qi, Shihua Cao, Bingsheng Wang, Ruihan Xie, Jiani Yao, Xiajing Lou, Chaoqun Dong, Xiaohong Zhu, Danni He

“…The most influential predictors were educational level, total medication count, age, sbp and BMI.Conclusions The proposed classifier can help guide preclinical screening of AD in the elderly population.…”
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Blood Lipid Levels and Their Value as Markers of Disease Activity in Severe Ulcerative Colitis by Zhu L, Tian L, Li S, Huo L

“…This study aimed to explore the relationship between blood lipid levels and disease activity, and to evaluate the early predictive value of blood lipid levels for severe ulcerative colitis (UC).Patients and Methods: Here, we analyzed blood lipid indicators of 210 patients with UC and 210 healthy individuals who visited the hospital between August 2018 and August 2022. …”
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Safety and accuracy of digitally supported primary and secondary urgent care telephone triage in England: an observational study using routine data by Vanashree Sexton, Catherine Grimley, Jeremy Dale, Helen Atherton, Gary Abel

“…Methods Descriptive analyses were used to investigate outcomes of 98,946 calls that underwent primary and secondary triage. …”
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Impact of fetal sex on neonatal outcomes in women with gestational diabetes mellitus: a systematic review and meta-analysis by Mahsa Maghalian, Zohreh Alizadeh-Dibazari, Mojgan Mirghafourvand

“…Subgroup analyses differentiated between retrospective and prospective cohorts for the primary outcomes. Sensitivity analyses were performed using the leave-one-out approach to evaluate the robustness of the pooled results. …”
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Cost-effectiveness of selective digestive decontamination (SDD) versus selective oropharyngeal decontamination (SOD) in intensive care units with low levels of antimicrobial resist... by Marc J M Bonten, Denise van Hout, Nienke L Plantinga, Patricia C Bruijning-Verhagen, Evelien A N Oostdijk, Anne Marie G A de Smet, G Ardine de Wit, Cornelis H van Werkhoven

“…At a willingness-to-pay value of €33 633 per one prevented in-hospital death, SDD had a probability of 90.0% to be cost-effective as compared with SOD.Conclusion In Dutch ICUs, SDD has a very high probability of cost-effectiveness as compared to SOD. …”
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Estimation of evaporation in Andalusian reservoirs: Proposal of an index for the assessment and classification of dams by Santiago García-López, Marcia Salazar-Rojas, Mercedes Vélez-Nicolás, Jorge. M.G.P. Isidoro, Verónica Ruiz-Ortiz

“…The combination of both variables has allowed to estimate the mean monthly volume of water evaporated in each reservoir. Results were validated with isotopic content (¹⁸O and ²H) from selected reservoirs. …”
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Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses by Ying Xiong, Linpeng Yao, Jinglai Lin, Jiaxi Yao, Qi Bai, Yuan Huang, Xue Zhang, Risheng Huang, Run Wang, Kang Wang, Yu Qi, Pingyi Zhu, Haoran Wang, Li Liu, Jianjun Zhou, Jianming Guo, Feng Chen, Chenchen Dai, Shuo Wang

“…Both models outperform corresponding radiomics models and the nephrometry score nomogram. Here we show that the deep learning models can non-invasively predict the likelihood of malignant and aggressive pathology of a renal mass based on preoperative multi-phase CT images.…”
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Association Between Dietary Inflammatory Index and Triglyceride Glucose-Body Mass Index with Iron Deficiency in Reproductive Age Women: Evidence from NHANES 2005-2018 by Ding J, Xu Z, Liang R, Xie S

“…RCS analysis indicated that the relationships were mostly linear (P-overall < 0.05, P-nonlinear > 0.05). …”
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Validation of In-field Calibration for Low-Cost Sensors Measuring Ambient Particulate Matter in Kolkata, India by Siddharth Nobell, Arnab Majumdar, Shovon Mukherjee, Sukumar Chakraborty, Sanjoy Chatterjee, Soumitra Bose, Anindita Dutta, Sandhya Sethuraman, Daniel M. Westervelt, Shairik Sengupta, Rakhi Basu, V. Faye McNeill

“…Data from the co-locations were used to calibrate the LCS network using random forest regression and multiple linear regression approaches. …”
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Comparative effectiveness of laparoscopic versus open colectomy in colon cancer patients: a study protocol for emulating a target trial using cancer registry data by Semaw Ferede Abera, Gabriele Robers, Anika Kästner, Ulrike Stentzel, Kerstin Weitmann, Wolfgang Hoffmann

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Research progress on the structure of hydration films at solid–liquid interfaces by Na ZHANG, Jue KOU, Chunbao SUN

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