Toxic Effects of Hydroxyl- and Amine-functionalized Silica Nanoparticles (SiO2 and NH2-SiO2 NPs) on Caenorhabditis elegans by Danielle E. Que, Wen-Che Hou, Micah Belle Marie Yap Ang, Chih-Chung Lin

“…The chronic lethality and lifespan assays revealed a significant decrease in survival rate and lifespan at 2.5 and 5 mg mL−1 for nematodes exposed to bare SiO2 NPs (89% and 88%; 22 days, p < 0.05 and 14 days, p < 0.05) and at 5 mg mL−1 for the NH2-SiO2 NPs-exposed group (86%; 20 days, p < 0.001). …”
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Model Analisis Aktivitas Tutor Dalam Learning Management System Berdasarkan Data Log Menggunakan K-Means Dan Deteksi Outlier by Agusriandi Agusriandi, Elihami Elihami, Irman Syarif, Ita Sarmita Samad

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The AFFIRM Framework for gender-affirming care: qualitative findings from the Transgender and Gender Diverse Health Equity Study by Meg Quint, Schuyler Bailar, Alexis Miranda, Shalender Bhasin, Devin O’Brien-Coon, Sari L. Reisner

“…Results Participants had a mean age of 28.5, ranging 18–45 years, and were: 7 transgender men, 6 transgender women, 8 nonbinary, 3 genderqueer, 1 agender, and 2 gender not specified. …”
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Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation by Sören J. Backhaus, Alexander Schulz, Torben Lange, Simon F. Rösel, Lennart S. Schmidt-Schweda, Shelby Kutty, Johannes T. Kowallick, Julia Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenuß, Andreas Schuster

“…Clinicaltrials.gov: NCT03260621 (First posted date 24/08/2017).…”
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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases by Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

“…The TME of RCC brain metastases, a major cause of morbidity, also remains largely uncharacterized.Methods We performed digital spatial profiling on the NanoString GeoMx platform using 52 validated immuno-oncology markers on RCC tissue microarrays representing progressive stages of RCC, including brain metastases. We profiled 76 primary tumors, 27 adjacent histologically normal kidney samples, and 86 metastases, including 24 brain metastases.Results We observed lower immune checkpoint (TIM-3 and CTLA-4), cytolytic (GZMA and GZMB), and T cell activation (CD25) protein expression in metastases compared with primary tumors in two separate cohorts. …”
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Трикомпонентна модель психопрофілактики посттравматичного стресового розладу у дітей дошкільного віку... by Олена Нагула, Леонід Ніколаєв

“…Зафіксовано суттєве зниження частоти дезадаптивних поведінкових проявів: тривожної поведінки на 64% (з 50 до 18 випадків), агресивних реакцій на 71% (з 31 до 9 випадків), проявів невпевненості на 86% (з 43 до 6 випадків), різких змін настрою на 76% (з 38 до 9 випадків). …”
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Evaluation and Management of Patients with Hematoma After Gynecologic and Obstetric Surgery by Bekir Kahveci, Mehmet Obut, Serhat Ege, Mete Sucu, Nurullah Peker, Osman Uzundere, Gaye Kahveci, Mehmet Sukru Budak

“…The mean time of resorption of the hematoma was 4.6 ± 2.0 days. The evaluation of the hematoma locations revealed that 14 patients (46.7%) had wound hematoma, 7 patients (23.3%) had rectus sheath hematoma (Type I: 2 cases, type II: 3 cases, type III: 2 cases), 8 patients (26.7%) had pelvic hematoma and 2 patients (6.7%) had a retroperitoneal hematoma. …”
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Trends and Variability of PM2.5 at Different Time Scales over Delhi: Long-term Analysis 2007–2021 by Chetna, Surendra K. Dhaka, Gagandeep Longiany, Vivek Panwar, Vinay Kumar, Shristy Malik, A. S. Rao, Narendra Singh, A. P. Dimri, Yutaka Matsumi, Tomoki Nakayama, Sachiko Hayashida

“…The average concentration of PM2.5 in the study period of 15 years remained 125 ± 86 µg m−3 (ranging between 20 to 985 µg m−3) and during winter, summer, monsoon, and post-monsoon seasons it was 174 ± 75, 101 ± 48, 66 ± 50, and 192 ± 93 µg m−3 respectively. …”
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Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City by Liyan Ma, Dongmei Hu, Yulong Yan, Yueyuan Niu, Xiaolin Duan, Yafei Guo, Wanhua Li, Lin Peng

“…The OC and EC concentrations and annual average ratio of OC/EC in Jincheng were 5.54 µg m−3, 0.98 µg m−3, and 5.67, respectively. The concentration change in carbonaceous components shows strong seasonality and daily variation characteristics, and the influence of biomass combustion on carbonaceous components in winter cannot be ignored. …”
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Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease by Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li

“…Moreover, T helper type 17 cells, natural killer cells and CD56dim natural killer cells were significantly correlated with biomarkers. …”
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Efficacy and safety of first-line nivolumab plus ipilimumab treatment in elderly patients (aged ≥ 75 years) with non-small cell lung cancer by Satoshi Endo, Hisao Imai, Atsuto Mouri, Kasumi Tsukamoto, Kenji Masaki, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Junichi Nakagawa, Kyoichi Kaira, Kunihiko Kobayashi, Hiroshi Kagamu

“…Results The overall response rate was 42.1%, the disease control rate was 73.6%, the median progression-free survival (PFS) was 7.1 months, and the median overall survival (OS) was 14.1 months. …”
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Enhanced effect of radiofrequency ablation on HCC by siRNA-PD-L1-endostatin Co-expression plasmid delivered by Pengfei Chen, Kun Li, Jinwei Chen, He Hei, Jiaxin Geng, Nannan Huang, Mengyu Lei, Huijie Jia, Jianzhuang Ren, Chenwang Jin

“…Additionally, it induced tumor cell apoptosis, inhibited proliferation and migration, and increased the infiltration of T lymphocytes, granzyme B+ T cells, and CD86+macrophages within tumors. There was also a notable rise in T and NK cell populations in the spleen. …”
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Assessment of Knowledge, Attitude and Practices of Health Workers Towards Hepatitis B Virus Infection Prevention in Health Centers of Bushenyi District. by Byamukama, Julius

“…Whereas, a significant number of health workers, 66 (26.8 %), had been exposed to blood/body fluid through needle stick injuries at least once since they started their duties in the health facility. …”
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Metode COPRAS untuk Menentukan Kain Terbaik dalam Pembuatan Pakaian pada Butik Batik Hatta Semarang by Saifur Rohman Cholil, Mohamad Adi Setyawan

“…Hasil uji koefisien Spearman Rank diperoleh nilai sebesar 0.866% artinya metode ini layak untuk digunakan.   …”
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Validity and reliability of the Manchester Oxford Foot Questionnaire (MOXFQ) in one-year postoperative ankle fracture patients—a validation study by Michael Quan Nguyen, Marjolein Memelink Iversen, Knut Harboe, Ingvild Dalen, Aksel Paulsen

“…The domains had good internal consistency (McDonald’s omega 0.80 to 0.95) and test-retest reliability (ICC 0.80 to 0.92). …”
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Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease by Yue Xu, Yue Xu, Durong Chen, Meiqi Dong, Yun Zhang, Yun Zhang, Hongmei Yu, Hongmei Yu, Hongmei Yu, Yanqing Han, Yanqing Han, Yanqing Han

“…Then, we explored the mediating role of cognitive function in the bidirectional relationship between depression and ADL in patients with PD, and the mediation effect test was carried out using a bias-corrected nonparametric percentile bootstrap approach.ResultsDepression in patients with PD predicted their subsequent ADL (β = 0.079, p &lt; 0.01), and ADL also predicted their subsequent depression (β = 0.069, p &lt; 0.05), In addition, Bootstrap analysis showed that cognitive function played a significant mediating role in prediction of depression to ADL in patients with PD (β = 0.006, p = 0.074, 95%CI = 0.001 ~ 0.014), and cognitive function also played a significant mediating role in prediction of depression to ADL (β = 0.006, p = 0.067, 95%CI = 0.001 ~ 0.013).ConclusionThere is a bidirectional relationship between depression and ADL in patients with PD. …”
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Penerapan Metode Simple Additive Weighting dalam Pemeringkatan Kinerja Keuangan Perusahaan Sektor Teknologi yang Terdaftar di Bei by I Made Satya Sundara, I Gst. Agung Pramesti Dwi Putri, I Nyoman Yudi Anggara Wijaya

“…Jumlah alternatif yang digunakan pada penelitian ini berjumlah 8 alternatif. Hasil penelitian ini adalah perusahaan MLPT sebagai perusahaan dengan kinerja keuangan terbaik dalam sektor teknologi dengan nilai tertinggi yaitu 0.866. …”
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Analisis Sentimen terhadap Kebijakan Kuliah Daring Selama Pandemi Menggunakan Pendekatan Lexicon Based Features dan Support Vector Machine by Natasya Eldha Oktaviana, Yuita Arum Sari, Indriati Indriati

“…Penggunaan Lexicon Based Features berpengaruh terhadap objek penelitian yang menghasilkan nilai accuracy 0,6, nilai precision 0,56, nilai recall 0,75, dan fmeasure 0,64 dengan parameter optimal dalam mencapai konvergensi yaitu ???? …”
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Nematode Management Using Sorghum and Its Relatives by K. Dover, Koon-Hui Wang, Robert McSorley

“…Moench) and sorghum-sudangrass (S. bicolor x S. sudanense (Piper) Stapf) are often used in crop rotation systems in Florida. …”
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The Application of Maqasid al-Shariah in the Development of Women's Leadership Model in Malaysia by Atriza Umar, Hamidah Mat

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