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4522
Imaging flow cytometry-based cellular screening elucidates pathophysiology in individuals with Variants of Uncertain Significance
Published 2025-02-01“…Assay sensitivity was verified with compounds (N = 5) and positive control patients (N = 6). Eight healthy controls and 20 individuals with VUS were screened. …”
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4523
Impact of hepatic steatosis on the efficacy of antiviral treatment for chronic hepatitis B and the establishment of predictive model: a cohort study
Published 2025-02-01“…Results At weeks 24 and 48, the CHB + MASLD group displayed a higher HBsAg response rate than the CHB group (24 weeks: 11.5% vs. 3.8%, p = 0.026; 48 weeks: 24.4% vs. 8.4%, p = 0.001). …”
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4524
Spatial distribution and determinants of children ever born among reproductive age women in Ethiopia: spatial and multilevel analysis of 2019 mini Ethiopian demographic health surv...
Published 2025-02-01“…Adjusted odds ratio AOR) with a 95% confidence interval (CI) was used to show the strength and direction of the association respectively.ResultsHigh number of CEB in Ethiopia was 37.46%, 95% CI (0.39–0.56) and it was spatially clustered (Moran's index = 0.59 P value <0.0001). …”
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4525
Intelligent fault diagnosis method for rolling bearings based on flexible residual neural network
Published 2025-03-01“…In challenging environments with a signal-to-noise ratio of –6 dB, the proposed model achieves a fault diagnosis accuracy of 97.18%, proving its strong noise resistance. …”
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4526
Effect of drinking water salinity on lactating cows’ water and feed intake, milk yield, and rumen physiology
Published 2025-02-01“…Following 2 weeks of adaptation to individual feeders and troughs, four Israeli Holstein multiparous lactating cows were offered, in a Latin square design, drinking water with EC levels of 400, 600, 800 or 1 000 µS/cm, through addition of concentrated NaCl solutions (measured EC in troughs averaged 418, 624, 811, and 1 016 µS/cm and 209, 312, 406, and 508 TDS ppm, respectively), for four periods of 18 days each. …”
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4527
Novel Procedures for Evaluating Autism Online in a Culturally Diverse Population of Children: Protocol for a Mixed Methods Pathway Development Study
Published 2025-02-01“…Quantitative usability assessment will be gathered from all families using the System Usability Scale (where a mean above 68 indicates above-average usability). A subset of CHATA assessments will be reviewed for interrater reliability (measured by the Cohen κ for categorical data [diagnosis present or absent], with values indicating the level of agreement; eg, <0 indicating no agreement, 0.61-0.80 indicating substantial agreement). …”
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4528
Pre-exposure Prophylaxis Awareness and Endorsement among Adolescents and Young Adults in Tanzania: Insights from the 2022 Demographic and Health Survey
Published 2025-01-01“…The odds of AYA endorsement of PrEP were higher among those aged 20–24 years versus 15–19 years (aOR = 1.39; 95% CI 1.07–1.83) and those who previously tested for HIV and received results (aOR = 1.97; 95% CI 1.43–2.72), but lower among female respondents (aOR = 0.66; 95% CI 0.49–0.88). …”
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4529
Antiemetic activity of Sesamol possibly through serotonergic and dopaminergic receptor interaction pathways: In vivo and in silico studies
Published 2025-03-01“…Additionally, SEL can antagonize the activity of ondansetron (OND; 5 mg/kg) and domperidone (DOM; 7 mg/kg), resulting in a decrease in latency (256.00 ± 9.59 and 253.00 ± 2.79 s) and enhancing the number of retches (11.80 ± 0.82 and 12.60 ± 1.04) in combination rather than OND and DOM alone. …”
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4530
Point-of-care tests in the emergency medical services: a scoping review
Published 2025-02-01“…The majority of research was done in the UK (19%), US (17%), and the Netherlands (16%), mostly in land-based EMS (82%). Most frequently assessed were troponin for acute coronary syndromes (26%), lactate for sepsis (14%) or lactate for trauma/critical illness (13%). …”
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4531
The ASK-16 motorized glider: an airborne eddy covariance platform to measure turbulence, energy, and matter fluxes
Published 2025-02-01“…The uncertainty of <span class="inline-formula"><i>w</i></span> is between 0.15 and 0.27 m s<span class="inline-formula"><sup>−1</sup></span> (median <span class="inline-formula">=</span> 0.23 m s<span class="inline-formula"><sup>−1</sup></span>), and the uncertainty of <span class="inline-formula"><i>u</i></span> and <span class="inline-formula"><i>v</i></span> ranges between 0.16 and 0.55 m s<span class="inline-formula"><sup>−1</sup></span> (median <span class="inline-formula">=</span> 0.25 m s<span class="inline-formula"><sup>−1</sup></span>). …”
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Search for a charged Higgs boson decaying into top and bottom quarks in events with electrons or muons in proton-proton collisions at s $$ \sqrt{\mathrm{s}} $$ = 13 TeV
Published 2020-01-01“…The data are compatible with the standard model, and 95% confidence level upper limits of 9.6–0.01 pb are set on the charged Higgs boson production cross section times branching fraction to a top-bottom quark-antiquark pair, for charged Higgs boson mass hypotheses ranging from 200 GeV to 3 TeV. …”
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Factors influencing in-hospital mortality for salvage percutaneous transjugular intrahepatic portosystemic shunting in cirrhotic patients with recalcitrant variceal bleeding after...
Published 2023-12-01“…Univariate logistic regression analysis showed that the most significant predictors of mortality were inotrope dependency (odds ratio (OR) 134; p<0.001), endotracheal intubation (OR 99; p<0.001), endoscopically uncontrolled bleeding (OR 28; p=0.001), grade 3 ascites (OR 20.9; p=0.012) and C-P grade C (OR 8.8; p=0.011). …”
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4536
Improved SED-fitting Assumptions Result in Inside-out Quenching at z ~ 0.5 and Quenching at All Radii Simultaneously at z ~ 1
Published 2025-01-01“…Their slopes are similar at all masses (0.06–0.08 dex kpc ^−1 ), and the normalizations for the quiescent galaxies are lower. …”
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4537
Treating drug-resistant tuberculosis in an era of shorter regimens: Insights from rural South Africa
Published 2023-11-01“…Injectables (adjusted odds ratio (aOR) 3.00, 95% confidence interval (CI) 1.48 - 6.09), bedaquiline (aOR 3.16, 95% CI 1.36 - 7.35), increasing age (aOR 0.97, 95% CI 0.95 - 0.99) and HIV viraemia defined as final HIV-RNA viral load >1 000 copies/mL (aOR 0.16, 95% CI 0.07 - 0.37) were all significantly and independently associated with treatment success. …”
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4538
Evaluación del Sistema Acuapónico de Pequeña Escala para la Producción de Tilapia y Lechuga
Published 2024-09-01“…Como resultado los valores de calidad del agua fueron 7.4 mg L-1 para oxígeno disuelto, 0.028 mg L-1 nitrógeno amoniacal, 29 mg L-1 nitrógeno de nitrato, 597 µS cm-1 de conductividad eléctrica, 15 mg L-1 de solidos suspendidos, 349 mg L-1 de solidos disueltos totales; en la demanda bioquímica de oxígeno en los tanques de peces fue de 7.1 mg L-1, en los filtros 8.9 mg L-1 y en las balsas 8.5 mg L-1 respectivamente. …”
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4539
Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway
Published 2025-02-01“…Results: The WLE relaxed PA (EC50=4.96±0.81µg/ml) more than the aorta (EC50=27.50±7.61µg/ml, p < 0.001), suggesting its selectivity on the PA vs the aorta. …”
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NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model
Published 2025-02-01“…Antitumor effect was abolished upon in-vivo depletion of CD8-T, macrophages, and CD4-T cells whereas remained unaffected upon NK-cell depletion. …”
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