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  1. 4861

    Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

    Published 2025-02-01
    “…Target screening by network pharmacology yielded a total of 236 active ingredients of Baji capsule, as well as 278 common targets after taking the intersection of Baji capsule active ingredient targets and osteoporosis disease-related targets.Conclusion: Baji capsule can treat osteoporosis by reducing inflammation and oxidative stress. …”
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  2. 4862
  3. 4863

    Optimization of Wall-disruption Process of Rose Bee Pollen and Comparison of Physiological Activities of Its Ethanol Extracts by Xinyang LU, Yishu SUN, Tao XU, Longbin FAN, Yaning CHANG, Yingjun ZHOU

    Published 2025-02-01
    “…The active substances extracted with 90% ethanol could significantly (P<0.01) reduce the release level of inflammatory factors induced by lipopolysaccharide in RAW264.7 cells (at 20 μg/mL, compared with the model group, nitric oxide, interleukin-6 and tumor necrosis factor-α decreased by 67.04%, 16.74% and 21.74% respectively), and had the most obvious inhibitory effect on the activity and proliferation of BPH-1 cells, thus exhibiting optimal anti-inflammatory and anti-BPH effects. …”
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  4. 4864
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  7. 4867
  8. 4868

    Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis by Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu

    Published 2025-02-01
    “…Methods and results A case-control study was conducted with 17 cases diagnosed with non-syndromic CHDs (CHDs group) and 34 controls without congenital anomalies (control group) at a ratio of 1:2. The 16 S rDNA gene sequencing and metabolomics methods were employed to assess 51 amniotic fluid samples. …”
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  9. 4869
  10. 4870

    Fine Particle pH and its Impact on PM2.5 Control in a Megacity of Central China by Mingming Zheng, Ke Xu, Lianxin Yuan, Nan Chen, Menghua Cao

    Published 2022-04-01
    “…Moderate PM2.5 acidity was found in Wuhan, a megacity of Central China, wherein 80% of PM2.5 hold pH values ranging from 2–4. Total ammonia (NHx) and sulfate contributed 79.1–93.7% to pH changes in spring and winter, while relative humidity was the largest contributor (33.7–36.3%) in summer and fall. …”
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  11. 4871
  12. 4872
  13. 4873
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  15. 4875

    Airway microbiota dysbiosis and metabolic disorder in ozone and PM2.5 co-exposure induced lung inflammatory injury in mice by Lin Yang, Fei Xu, Shuaiqi Zhao, Yuling Zeng, Qiong Wu, Ling Zhang, Saige Shi, Fengquan Zhang, Juan Li, Zhen An, Huijun Li, Hui Wu, Jie Song, Weidong Wu

    Published 2025-01-01
    “…The scenario for O3 exposure was 0.6 ppm, 4 h/d, for 30 consecutive days while that for PM2.5 exposure was oral inhalation of PM2.5 suspension (5.6 mg/kg bw) once every other day and 4 h prior to O3 exposure. …”
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  16. 4876
  17. 4877

    Steroids In caRdiac Surgery (SIRS) trial: acute kidney injury substudy protocol of an international randomised controlled trial by Michael Walsh, Salim Yusuf, Chirag Parikh, Jessica Vincent, P J Devereaux, Francois Lamontagne, Matthew T V Chan, Richard Whitlock, Meaghan Cuerden, Amit X Garg, Andre Lamy, Daniel I Sessler, Kevin Teoh, Ainslie Hildebrand, Yunxia Zuo, Pallav Shah, Seyed Hesameddin Abbasi, Mackenzie Quantz, Jean-Pierre Yared, Nicolas Noiseux, Georgios Tagarakis, Antoine Rochon, Janice Pogue, Abbas Salehiomran

    Published 2014-03-01
    “…At the time of surgery, compared with placebo, methylprednisolone divided into two intravenous doses of 250 mg each may reduce the risk of postoperative acute kidney injury (AKI).Methods and analysis With respect to the study schedule, over 7000 substudy eligible patients from 81 centres in 18 countries were randomised in December 2013. …”
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  18. 4878
  19. 4879

    Identifying and ranking indicators affecting the environment with the aim of providing a guide on the establishment and operation of exhibition sites using BWM multi-criteria decis... by Davoud Adineh, Reza Amirnezhad, Keyvan Saeb, Aptin x Aptin Rahnavard, Farid Gholamreza Fahimi

    Published 2024-12-01
    “…The environmental index of the region was thus selected as the most important criterion whereas the social and economic indices were determined to be the least important criteria. Moreover, 58 sub-indices of the main indices were also weighed and prioritized based on the pairwise comparison. …”
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  20. 4880