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Multicenter study for CH-VAD as a fully magnetically levitated left ventricular assist device
Published 2025-02-01“…Patients had a mean age of 57.5 years, primarily classified as INTERMACS 2 or 3, with dilated and ischemic cardiomyopathy as the main causes of heart failure (HF). The study reported a 91.6% survival rate at both 6-month and 1-year follow-ups, aligning with international LVAD outcomes. …”
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Packed bed optofluidic microreactors with Au decorated TiO2 nanoflowers for visible light photocatalytic water purification
Published 2025-02-01“…Compared to TNFs in slurry-mode, the Au/TNFs achieve 46-fold enhancement in photodegradation efficiency due to the plasmonic effect, further boosted to 2,700-fold enhancement in the PPOM configuration by improving surface area, light harvesting, and mass transfer. …”
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Levels, Chemical Compositions, and Sources of PM2.5 of Rural and Urban Area under the Impact of Wheat Harvest
Published 2021-04-01“…Between DWH and AWH, the share of soil dust in the PM2.5 decreased from 21.3% to 7.98% and from 9.40% to 6.75% at ARS and UA, respectively. …”
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Engineering a promiscuous prenyltransferase for selective biosynthesis of an undescribed bioactive cannabinoid analog
Published 2025-02-01“…Compound 4 demonstrates the highest anti-neuroinflammatory and antibacterial activities, with IC50 values of 3.06 µM for TNF-α and 4.31 µM for IL-6, alongside EC50 values ranging from 0.87 to 3.16 µM against three Gram-positive bacteria. …”
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Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer
Published 2025-02-01“…We also generated a single-cell transcriptomic atlas of TLS-positive (n = 4) and TLS-negative (n = 8) microenvironments and performed spatial transcriptomics (ST) analysis on two samples. …”
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Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study
Published 2025-02-01“…Results Analysis of the pooled MR results and after correction for the false discovery rate (FDR) revealed that five lipid levels were associated with DR risk. Phosphatidylcholine (16:0_16:0) levels [OR = 0.869 (0.810 to 0.933), P fdr = 0.006], phosphatidylcholine (16:0_20:2) levels [OR = 0.893 (0.834 to 0.956), P fdr = 0.043] and phosphatidylethanolamine (18:0_20:4) levels [OR = 0.906 (0.863 to 0.951), P fdr = 0.006] were protective against DR, whereas sphingomyelin (d36:1) levels [OR = 1.120 (1.061 to 1.183), P fdr = 0.006], and sphingomyelin (d40:1) levels [OR = 1.081 (1.031 to 1.134), P fdr = 0.043] were associated with a greater risk of DR. …”
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Manipulation of seed coat content for increasing oil content via modulating BnaMYB52 in Brassica napus
Published 2025-02-01“…Knocking out BnaMYB52 results in a 7.7%–8.2% reduction in seed coat content (SCC) but a 12.3%–13.4% increase in SOC, whereas overexpression of BnaA09.MYB52 leads to the opposite effects. …”
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Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents
Published 2025-02-01“…Molecular modelling studies suggested the ability of compounds 9m and 9o to establish interactions with three hydrogen bonds to Asp267 and Glu346 of NHE-1, but also the ability with much lower CDOCKER energies than positive control cariporide and buthutin A. …”
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Geographical origin discrimination of Chenpi using machine learning and enhanced mid-level data fusion
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Genomic insights into ecological adaptation of oaks revealed by phylogenomic analysis of multiple species
Published 2025-01-01“…Here we used a newly sequenced genome of Quercus gilva, an evergreen oak species from East Asia, with 18 published Fagales genomes to determine how Fagaceae genomes have evolved, identify genomic footprints of ecological adaptability in oaks in general, as well as between evergreen and deciduous oaks. …”
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EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma
Published 2025-02-01Subjects: Get full text
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Tracing the change of the volatile compounds of soy sauce at different fermentation times by PTR-TOF-MS, E-nose and GC–MS
Published 2025-01-01“…Food Chemistry: X…”
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Baseline atherogenic index of plasma and its trajectory predict onset of type 2 diabetes in a health screened adult population: a large longitudinal study
Published 2025-02-01“…The LCTM identified three trajectory patterns for AIP: with the low-stable group as the reference, the medium-stable and high-stable groups had HRs of 1.72 (95% CI: 1.50, 1.96) and 2.50 (95% CI: 2.06, 3.03), respectively, indicating a significantly elevated risk of T2DM (P < 0.05). …”
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The mediating role of social support in self-management and quality of life in patients with liver cirrhosis
Published 2025-02-01“…Social support had a mediating effect between self-management and quality of life, with an indirect effect of 0.489 (95% CI: 0.362, 0.629), accounting for 40.58% of the total effect. (4) Exercise frequency and malnutrition risk assessment were independent influencing factors for social support, self-management, and quality of life. (5) In the regression model, after excluding confounding factors, Model I explained 14% of the variance in quality of life due to control variables, Model II explained 49.5%, and when social support was added, Model III explained 56.9% of the variance in quality of life. …”
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