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  1. 1081
  2. 1082

    Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

    Published 2025-01-01
    “…ProspectsThis study posits seven development directions for deep CBM production and in-situ coal conversion experiments: (1) Clear, direct observation techniques for micropores (< 2 nm) in deep coal seams with ultra-low porosity and permeability, full-scale pore size splicing technology for multiscale pore structure characterized by abundant micropores, a few mesopores, and many macropores, and assessment techniques for pore-fracture connectivity. (2) Isothermal adsorption test technologies for raw coals considering the effects of deep coal seam wettability, fracturing fluid invasion, and high total dissolved solids (TDS) under high-temperature, high-pressure in-situ conditions; (3) Sealed coring devices and in-situ pressure-retaining coring technologies featuring high pressure retaining success rates, heat preservation rates, and traceable gas volume. (4) Nanoscience-based assessment technologies for gas and water occurrence in micropores in deep coal seams under high-temperature and high-pressure multi-field coupling, and experimental technologies for desorption, diffusion, and seepage across nano-micro-millimeter scales. (5) Techniques for developing and testing multifunctional mechanical experiment equipment applicable to in-situ conditions of deep coal seams featuring high stress, low modulus of elasticity, and high Poisson's ratio. (6) Experimental techniques for the purpose of enhancing CBM recovery of deep coal seams, including reservoir stimulation (microwaves, laser, and electric heating), stimulation for permeability enhancement (electromagnetic pulses, pulsed ultrasonic waves, and controlled shockwaves), displacement via CO2 injection, and mechanical pulsation with supercritical CO2. (7) Experimental techniques for in-situ coal conversion and utilization, including pyrolysis, underground coal gasification (UCG), geothermal utilization, and CO2 geological storage. …”
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  3. 1083

    Exposure to nano-polystyrene during pregnancy leads to Alzheimer's disease-related pathological changes in adult offspring by Fengxu Wang, Jin Wang, Na Luo, Yonghua Luo, Zhengnan Gao, Ye Cui, Mengna Jiang, Zhaoping Shen, Jing Xiao, Peng Xue, Xiaoke Wang, Shali Yu, Qiyun Wu, Xinyuan Zhao

    Published 2025-01-01
    “…Throughout the research, we assessed the AD pathology in adult offspring of mice prenatal 80 nm polystyrene nanoparticles (PS-NPs) exposure. …”
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  4. 1084
  5. 1085

    Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

    Published 2025-02-01
    “…Results For the 53 nodule samples from 26 MPLCs patients, EGFR was the mostly mutated genes, and the TP53 mutation frequency was notably different between major and minor nodules. …”
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  6. 1086
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  10. 1090

    Metabolic syndrome in type 1 diabetes: higher time above range and glycemic variability revealed by continuous glucose monitoring (CGM) by Yayu Fang, Wei Liu, Xiaoling Cai, Yu Zhu, Mingxia Zhang, Siqian Gong, Xiangqing Wang, Chu Lin, Rui Zhang, Sai Yin, Juan Li, Yongran Huo, Xiaodan Hu, Xiaoqi Xie, Linong Ji

    Published 2025-02-01
    “…The comparison of CGM metrics suggested significantly higher time above range (TAR, 48.9%, IQR 35.3–59.5 vs. 32.8%, IQR 16.1–47.6; P < 0.001), standard deviation (SD, 3.6 ± 0.9 mmol/L vs. 3.2 ± 1.0 mmol/L; P = 0.022) and interquartile range (IQR, 4.2 mmol/L, IQR 3.2–4.8 vs. 3.7 mmol/L, IQR 3.0-4.5; P = 0.046) in those with metabolic syndrome. …”
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  11. 1091
  12. 1092

    Remote sensing-based maize growth process parameters revel the maize yield: a comparison of field- and regional-scale by Minghan Cheng, Xiuliang Jin, Chenwei Nie, Kaihua Liu, Tianao Wu, Yuping Lv, Shuaibing Liu, Xun Yu, Yi Bai, Yadong Liu, Lin Meng, Xiao Jia, Yuan Liu, Lili Zhou, Fei Nan

    Published 2025-02-01
    “…The results indicate that the four process parameters extracted in this study can accurately estimate crop yields, with rRMSE = 14.08% at the field-scale and rRMSE = 17.75% at the regional-scale. …”
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  13. 1093
  14. 1094

    Tear glucose is associated with the presence and severity of diabetic retinopathy by Ningyao Cao, Lili Feng, Wei Xu, Fanglin He, Caiwen Xiao, Yan Liu, Weirong Xu, Jingjing Cui, Yuqian Guo, Lianqing Yao, Wenwen Xia, Fei Chen, Yong Li, Chuandi Zhou, Xiaofang Xu

    Published 2025-02-01
    “…Moreover, Spearman’s correlation analysis suggested that the grading of TG increased with the severity of DR (rs = 0.28, p < 0.01). The area under the curve (AUC) of the model integrating TG, the duration of diabetes and HbA1c was 0.76 (95% CI 0.69–0.84), indicating a fair discriminative ability of DR. …”
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  17. 1097

    Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin by Ziwei Yang, Ziwei Yang, Tixin Han, Ruibin Yang, Ruibin Yang, Yinuo Zhang, Yinuo Zhang, Yifei Qin, Yifei Qin, Yifei Qin, Jialu Hou, Jialu Hou, Fei Huo, Fei Huo, Zhuan Feng, Zhuan Feng, Yaxin Ding, Yaxin Ding, Jiali Yang, Jiali Yang, Gang Zhou, Gang Zhou, Shijie Wang, Shijie Wang, Xiaohang Xie, Xiaohang Xie, Peng Lin, Peng Lin, Zhi-Nan Chen, Zhi-Nan Chen, Jiao Wu, Jiao Wu

    Published 2025-02-01
    “…The inhibition of the cystine-glutamate antiporter, system Xc–, induces ferroptosis. Imidazole ketone erastin (IKE), an inhibitor of the system Xc– functional subunit solute carrier family 7 member 11 (SLC7A11), is an effective and metabolically stable inducer of ferroptosis with potential in vivo applications. …”
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    How Europe Underdeveloped Africa / by Rodney, Walter

    Published 1972
    “…Europe Colonies Africa Economic policy. 2286…”
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