In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives

In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives

Melanoma is the most aggressive and lethal type of skin cancer, responsible for approximately 60,000 deaths annually. The main strategy for treating melanoma is surgery to completely remove the lesion and its margins. However, for more advanced cases with a high recurrence rate, the preferred approa...

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Main Authors: Héverton Mendes Araújo, Gabriel Acácio de Moura, Yasmim Mendes Rocha, Cristian Vicson Pinheiro Gomes, Valentina Nascimento e Melo de Oliveira, Ronaldo Nascimento de Oliveira, Larissa Deadame de Figueiredo Nicolete, Emanuel Paula Magalhães, Ramon R.P.P.B. de Menezes, Roberto Nicolete
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
1,2,4 oxadiazole
Macrophages
Polarization
Murine melanoma
Immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825000378
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