Multi-organ frailty is enhanced by periodontitis-induced inflammaging

Multi-organ frailty is enhanced by periodontitis-induced inflammaging

Abstract Background The incidence of periodontitis is high in older individuals. However, its impact on multi-organ frailty remains unclear. We developed mouse models with varying severity and duration of periodontitis to examine its effects. Methods We generated mouse models with mild and severe pe...

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Main Authors: Yoshitaka Kase, Satoru Morikawa, Yuji Okano, Tatsuya Hosoi, Takazumi Yasui, Yoko Taki-Miyashita, Mitsutaka Yakabe, Maraku Goto, Kazuyuki Ishihara, Sumito Ogawa, Taneaki Nakagawa, Hideyuki Okano
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Inflammation and Regeneration
Subjects:
Inflammaging
Periodontitis
Frailty
Osteopenia
Cognitive decline
Cognitive frailty
Online Access:https://doi.org/10.1186/s41232-025-00366-5
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https://doi.org/10.1186/s41232-025-00366-5

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