Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review
Hemoglobin A1c is a widely used diagnostic tool for monitoring glycemic control in diabetes management. However, its accuracy can be influenced by various factors. We present a case of a 17-year-old boy with abnormally low Hemoglobin A1c levels caused by warm autoantibody-induced hemolytic anemia. T...
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Frontiers Media S.A.
2025-01-01
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Series: | British Journal of Biomedical Science |
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Online Access: | https://www.frontierspartnerships.org/articles/10.3389/bjbs.2024.13898/full |
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author | Sajjad Bakhtiari Nathan E. Timbrell Sènan M. D’Almeida |
author_facet | Sajjad Bakhtiari Nathan E. Timbrell Sènan M. D’Almeida |
author_sort | Sajjad Bakhtiari |
collection | DOAJ |
description | Hemoglobin A1c is a widely used diagnostic tool for monitoring glycemic control in diabetes management. However, its accuracy can be influenced by various factors. We present a case of a 17-year-old boy with abnormally low Hemoglobin A1c levels caused by warm autoantibody-induced hemolytic anemia. This case highlights the importance of considering conditions that may affect erythrocyte survival, and the potential interferences when interpreting Hemoglobin A1c results to ensure accurate diagnosis and effective management of diabetes. |
format | Article |
id | doaj-art-1a7ae11207d94d408ce5d45dc7b8481c |
institution | Kabale University |
issn | 2474-0896 |
language | English |
publishDate | 2025-01-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | British Journal of Biomedical Science |
spelling | doaj-art-1a7ae11207d94d408ce5d45dc7b8481c2025-02-06T17:31:40ZengFrontiers Media S.A.British Journal of Biomedical Science2474-08962025-01-018110.3389/bjbs.2024.1389813898Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature ReviewSajjad Bakhtiari0Nathan E. Timbrell1Sènan M. D’Almeida2Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranNutristasis Unit, Synnovis, Guy’s and St. Thomas’ NHS Trust, London, United KingdomViollier AG, Allschwil, SwitzerlandHemoglobin A1c is a widely used diagnostic tool for monitoring glycemic control in diabetes management. However, its accuracy can be influenced by various factors. We present a case of a 17-year-old boy with abnormally low Hemoglobin A1c levels caused by warm autoantibody-induced hemolytic anemia. This case highlights the importance of considering conditions that may affect erythrocyte survival, and the potential interferences when interpreting Hemoglobin A1c results to ensure accurate diagnosis and effective management of diabetes.https://www.frontierspartnerships.org/articles/10.3389/bjbs.2024.13898/fullglycated hemoglobinHbA1chemolytic anemiaenzymatic methoddiabetes |
spellingShingle | Sajjad Bakhtiari Nathan E. Timbrell Sènan M. D’Almeida Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review British Journal of Biomedical Science glycated hemoglobin HbA1c hemolytic anemia enzymatic method diabetes |
title | Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review |
title_full | Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review |
title_fullStr | Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review |
title_full_unstemmed | Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review |
title_short | Abnormally Low HbA1c Caused by Hemolytic Anemia, a Case Report and Literature Review |
title_sort | abnormally low hba1c caused by hemolytic anemia a case report and literature review |
topic | glycated hemoglobin HbA1c hemolytic anemia enzymatic method diabetes |
url | https://www.frontierspartnerships.org/articles/10.3389/bjbs.2024.13898/full |
work_keys_str_mv | AT sajjadbakhtiari abnormallylowhba1ccausedbyhemolyticanemiaacasereportandliteraturereview AT nathanetimbrell abnormallylowhba1ccausedbyhemolyticanemiaacasereportandliteraturereview AT senanmdalmeida abnormallylowhba1ccausedbyhemolyticanemiaacasereportandliteraturereview |