The effects of magnesium supplementation in autoimmune rheumatic diseases

Magnesium is an essential mineral for the human body, and its deficiency causes multiple detrimental cellular and organ dysfunctions. The issue of its routine supplementation is debatable, but there is no doubt that in case of depletion, it should be supplemented. Because of its role in i...

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Main Authors: Aaron Lerner, Jozélio Freire de Carvalho, Carina Benzvi, Motti Haimi
Format: Article
Language:English
Published: Academia.edu Journals 2024-11-01
Series:Academia Medicine
Online Access:https://www.academia.edu/125733588/The_effects_of_magnesium_supplementation_in_autoimmune_rheumatic_diseases
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author Aaron Lerner
Jozélio Freire de Carvalho
Carina Benzvi
Motti Haimi
author_facet Aaron Lerner
Jozélio Freire de Carvalho
Carina Benzvi
Motti Haimi
author_sort Aaron Lerner
collection DOAJ
description Magnesium is an essential mineral for the human body, and its deficiency causes multiple detrimental cellular and organ dysfunctions. The issue of its routine supplementation is debatable, but there is no doubt that in case of depletion, it should be supplemented. Because of its role in inflammatory and autoimmune conditions, its serum levels have been frequently analyzed. However, its role in rheumatological diseases has been barely investigated. The present review aims to screen the literature for well-designed studies in which magnesium was supplemented to cure rheumatological conditions. SciELO, PubMed, and Web of Science databases were screened between 1966 and April 2024 for the literature on this topic. Only one study fulfilled the inclusion criteria and demonstrated that 300 mg/day of oral magnesium reduced insulin resistance in rheumatoid arthritis patients. The lack of studies on this subject shows that additional studies are required to understand the causal relationship between magnesium supplementation and disease treatment.
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spelling doaj-art-1f2102cb1d154d05a97d812b603228de2025-02-11T23:30:20ZengAcademia.edu JournalsAcademia Medicine2994-435X2024-11-011410.20935/AcadMed7413The effects of magnesium supplementation in autoimmune rheumatic diseasesAaron Lerner0Jozélio Freire de Carvalho1Carina Benzvi2Motti Haimi3Research Department, The Zabludowicz Research Center for Autoimmune Diseases, Chaim Sheba Medical Center, Ramat Gan 52621, Israel.Núcleo de Pesquisa em Doenças Crônicas não Transmissíveis (NUPEN), School of Nutrition from the Federal University of Bahia, Salvador, Bahia 40110-040, Brazil.Research Department, The Zabludowicz Research Center for Autoimmune Diseases, Chaim Sheba Medical Center, Ramat Gan 52621, Israel.Health Administration Department, Yezreel Valley Academic College, D.N. Emek Yezreel 1930600, Israel. Magnesium is an essential mineral for the human body, and its deficiency causes multiple detrimental cellular and organ dysfunctions. The issue of its routine supplementation is debatable, but there is no doubt that in case of depletion, it should be supplemented. Because of its role in inflammatory and autoimmune conditions, its serum levels have been frequently analyzed. However, its role in rheumatological diseases has been barely investigated. The present review aims to screen the literature for well-designed studies in which magnesium was supplemented to cure rheumatological conditions. SciELO, PubMed, and Web of Science databases were screened between 1966 and April 2024 for the literature on this topic. Only one study fulfilled the inclusion criteria and demonstrated that 300 mg/day of oral magnesium reduced insulin resistance in rheumatoid arthritis patients. The lack of studies on this subject shows that additional studies are required to understand the causal relationship between magnesium supplementation and disease treatment.https://www.academia.edu/125733588/The_effects_of_magnesium_supplementation_in_autoimmune_rheumatic_diseases
spellingShingle Aaron Lerner
Jozélio Freire de Carvalho
Carina Benzvi
Motti Haimi
The effects of magnesium supplementation in autoimmune rheumatic diseases
Academia Medicine
title The effects of magnesium supplementation in autoimmune rheumatic diseases
title_full The effects of magnesium supplementation in autoimmune rheumatic diseases
title_fullStr The effects of magnesium supplementation in autoimmune rheumatic diseases
title_full_unstemmed The effects of magnesium supplementation in autoimmune rheumatic diseases
title_short The effects of magnesium supplementation in autoimmune rheumatic diseases
title_sort effects of magnesium supplementation in autoimmune rheumatic diseases
url https://www.academia.edu/125733588/The_effects_of_magnesium_supplementation_in_autoimmune_rheumatic_diseases
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