A transcriptional profile of aging in the human kidney.

A transcriptional profile of aging in the human kidney.

In this study, we found 985 genes that change expression in the cortex and the medulla of the kidney with age. Some of the genes whose transcripts increase in abundance with age are known to be specifically expressed in immune cells, suggesting that immune surveillance or inflammation increases with...

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Main Authors: Graham E J Rodwell, Rebecca Sonu, Jacob M Zahn, James Lund, Julie Wilhelmy, Lingli Wang, Wenzhong Xiao, Michael Mindrinos, Emily Crane, Eran Segal, Bryan D Myers, James D Brooks, Ronald W Davis, John Higgins, Art B Owen, Stuart K Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-12-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0020427&type=printable
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https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0020427&type=printable

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