A novel platform for engineered AAV-based vaccines
Engineering of adeno-associated virus (AAV) capsids allowed for the development of gene therapy vectors with improved tropism and enhanced transduction efficiency. Capsid engineering can also be used to adapt the AAV technology for applications outside gene therapy. Here, we investigated modified AA...
Saved in:
Main Authors: | Sabrina Babutzka, Miranda Gehrke, Anastasia Papadopoulou, Maria Diedrichs-Möhring, Maria Giannaki, Lena Hennis, Bastian Föhr, Cale Kooyman, Andreas Osterman, Evangelia Yannaki, Gerhild Wildner, Hermann Ammer, Stylianos Michalakis |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
|
Series: | Molecular Therapy: Methods & Clinical Development |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050125000130 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Fourlined Plant Bug Poecilocapsus lineatus (Fabricius) (Insecta: Hemiptera: Miridae)
by: Matthew Borden, et al.
Published: (2016-10-01) -
A new scheme for boosting in situ Fenton-like reaction in plant pathogenic tissues for selective structural degradation of capsid proteins
by: Jun Ma, et al.
Published: (2025-02-01) -
Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates
by: Mengping Liu, et al.
Published: (2025-03-01) -
Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution
by: Florian Dunker-Seidler, et al.
Published: (2025-03-01) -
The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression
by: Callan L. Attwell, et al.
Published: (2025-02-01)