Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis

Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis

Abstract Purpose Immune checkpoint blockades (ICBs) are promising, however they do not fit all types of tumor, such as those lack of tumor antigens. Induction of potent anti-tumor T cell immunity is critical for cancer therapy. In this study, we investigated the efficacy of immunotherapy via the imm...

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Main Authors: Min Hu, Xinyu Meng, Tong Wang, Yifan Wang, Xiaodong Chen, Dongliang Xu, Wei He, Hongjia Zhang, Wenzheng Guo, Bo Jing, Siwei Zhang, Jianhua Xu, Beibei Sun, Xueqian Sun, Tingting Liu, Na Ni, Tongtong Zhang, Wenwen Cui, Xiaoyu Wu, Liping Xia, Feng Yao, Fang Zhang, Jing Du, Jiong Deng
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Lung metastasis
Immunogenic cell death
Lung tumorigenesis
T cell immunity
Tumor vaccine
Online Access:https://doi.org/10.1007/s00432-025-06087-z
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https://doi.org/10.1007/s00432-025-06087-z

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