KLF5 promotes esophageal squamous cell carcinoma radioresistance by targeting the Keap1-Nrf2 pathway

KLF5 promotes esophageal squamous cell carcinoma radioresistance by targeting the Keap1-Nrf2 pathway

Abstract Objective Esophageal squamous cell carcinoma (ESCC) has high morbidity and mortality in developing countries. The purpose of this article is to study the mechanism of KLF5's effect on ESCC radiosensitivity. Methods WGCNA gene expression profiling identified core genes associated with E...

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Bibliographic Details
Main Authors: Yang Wang, Yue-ying Yang, Abulajiang Kamili, Dilimulati Aishanjiang, Yi Liu
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
Subjects:
Esophageal squamous cell carcinoma
KLF5
Keap1
Nrf2 pathway
Radiosensitivity
Online Access:https://doi.org/10.1007/s12672-025-01868-x
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https://doi.org/10.1007/s12672-025-01868-x

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