Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model

Engineered Bacillus subtilis WB600/ZD prevents Salmonella Infantis-induced intestinal inflammation and alters the colon microbiota in a mouse model

Abstract Antimicrobial peptides (AMPs) are instrumental in maintaining intestinal homeostasis and have emerged as potential therapeutic candidates for ameliorating intestinal bacterial infections. However, the intrinsic instability associated with the in vivo delivery of AMPs constitutes a substanti...

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Bibliographic Details
Main Authors: Wei Li, Xue Wang, Keyuan Chen, Yaohong Zhu, Guiyan Yang, Yipeng Jin, Jiufeng Wang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Veterinary Research
Subjects:
Zophobas atratus defensin
engineered bacteria
B. subtilis WB600/ZD
S. Infantis infection
small intestinal inflammation
Online Access:https://doi.org/10.1186/s13567-024-01438-z
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