Loss of YTHDC1 m6A reading function promotes invasiveness in urothelial carcinoma of the bladder

Abstract Bladder cancer poses significant clinical challenges due to its high metastatic potential and poor prognosis, especially when it progresses to muscle-invasive stages. Here, we show that the m6A reader YTHDC1 is downregulated in muscle-invasive bladder cancer and is negatively correlated wit...

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Bibliographic Details
Main Authors: Jinyun Xu, Jonas Koch, Claudia Schmidt, Malin Nientiedt, Manuel Neuberger, Philipp Erben, Maurice Stephan Michel, Manuel Rodríguez-Paredes, Frank Lyko
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01377-x
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