Plasma-derived extracellular vesicles prime alveolar macrophages for autophagy and ferroptosis in sepsis-induced acute lung injury

Abstract Sepsis-induced acute respiratory distress syndrome (ARDS) is a severe complication of sepsis and the leading cause of mortality. Although the role of alveolar macrophages (AMs) in stabilizing pulmonary homeostasis is well established, the effects of circulating extracellular vesicles (EVs)...

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Bibliographic Details
Main Authors: Rongzong Ye, Yating Wei, Jingwen Li, Yu Zhong, Xiukai Chen, Chaoqian Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-025-01111-x
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