FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2

Abstract Purpose Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. The Fat mass and obesity-associated protein (FTO), a genetic variant associated with obesity, significantly impact the energetic metabolism of mechanical tumors. However, research on the function of FT...

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Bibliographic Details
Main Authors: Kongyan Zhang, Fei Zhang, Jiahe Wang
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Online Access:https://doi.org/10.1007/s00432-024-06073-x
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