FTO effects the proliferation, invasion, and glycolytic metabolism of colon cancer by regulating PKM2
Abstract Purpose Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. The Fat mass and obesity-associated protein (FTO), a genetic variant associated with obesity, significantly impact the energetic metabolism of mechanical tumors. However, research on the function of FT...
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Main Authors: | Kongyan Zhang, Fei Zhang, Jiahe Wang |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-01-01
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Series: | Journal of Cancer Research and Clinical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00432-024-06073-x |
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