Tumor-associated macrophage-derived exosome miR-194 confers cisplatin resistance in GC cells

Abstract Objective At all stages of gastric cancer (GC), cisplatin is the first-line chemotherapeutic agent, but its efficacy remains limited, with a response rate of less than 20%, largely because of resistance to the drug. It aims to determine whether macrophage-derived exosomes are involved in th...

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Bibliographic Details
Main Authors: Yi Zhou, Yang-cheng Sun, Qiong-yan Zhang, Jing Wang, Xian-ya Zhu, Xiang-yu Su
Format: Article
Language:English
Published: BMC 2025-02-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02329-5
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