Hematological study of patients with recurrent aphthous stomatitis - Case control study
Background and Objectives: Recurrent aphthous stomatitis is common oral condition, characterized by multiple, recurrent, small, round, or ovoid ulcers with circumscribed, erythematous haloes, and yellow or grey floors. Its etiology and pathogenesis is not entirely clear linked to systemic diseases...
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| Format: | Article |
| Language: | English |
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College Of Dentistry Hawler Medical University
2021-07-01
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| Series: | Erbil Dental Journal |
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| Online Access: | https://edj.hmu.edu.krd/index.php/journal/article/view/111 |
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| author | Shaheen Ali Ahmed Ali Fakhree Alzubaidee |
| author_facet | Shaheen Ali Ahmed Ali Fakhree Alzubaidee |
| author_sort | Shaheen Ali Ahmed |
| collection | DOAJ |
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Background and Objectives: Recurrent aphthous stomatitis is common oral condition, characterized by multiple, recurrent, small, round, or ovoid ulcers with circumscribed, erythematous haloes, and yellow or grey floors. Its etiology and pathogenesis is not entirely clear linked to systemic diseases and among these, anemia, iron deficiency, folic- acid, and vitamin B12 deficiencies. The aim of this study to investigate the association between recurrent aphthous stomatitis and hemoglobin, serum ferritin, folic acid, and vitamin B12 deficiency.
Patient and Methods: This prospective cross sectional case control clinical study was conducted on 50 patients with recurrent aphthous stomatitis. The control group composed of 50 healthy age and sex-matched subject. The patient demography about family history of recurrent aphthous stomatitis, and smoking was recorded, also the hemoglobin, serum levels of ferritin, folic acid, and vitamin B12 has been investigated.
Results: The low hemoglobin was reported in 30% and vitamin B 12 deficiency in 31% of the patient so low hemoglobin and B12 deficiency have significant correlation with recurrent aphthous stomatitis. Patients with low hemoglobin, vitamin B12 deficiency , positive family history, and non smoker have been found to have the highest risk for having recurrent aphthous stomatitis.
Conclusion: Recurrent aphthous stomatitis is a multifactorial disease. Positive family history, low hemoglobin level , vitamin B12 deficiency, and nonsmoking status are among the important predisposing factors. Routine hematological screening and tests for iron status, folic acid, and vitamin B12 status should be assessed in all patients with recurrent aphthous stomatitis.
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| format | Article |
| id | doaj-art-4fae899b58ee4d729ad2b722ef683818 |
| institution | Kabale University |
| issn | 2523-6172 2616-4795 |
| language | English |
| publishDate | 2021-07-01 |
| publisher | College Of Dentistry Hawler Medical University |
| record_format | Article |
| series | Erbil Dental Journal |
| spelling | doaj-art-4fae899b58ee4d729ad2b722ef6838182025-02-10T20:48:37ZengCollege Of Dentistry Hawler Medical UniversityErbil Dental Journal2523-61722616-47952021-07-0141Hematological study of patients with recurrent aphthous stomatitis - Case control studyShaheen Ali Ahmed0Ali Fakhree Alzubaidee1Department of Oral and Maxillofacial Surgery, College of Dentistry, Hawler Medical University, Erbil, Iraq.Kurdistan Board of Medical Specialists Background and Objectives: Recurrent aphthous stomatitis is common oral condition, characterized by multiple, recurrent, small, round, or ovoid ulcers with circumscribed, erythematous haloes, and yellow or grey floors. Its etiology and pathogenesis is not entirely clear linked to systemic diseases and among these, anemia, iron deficiency, folic- acid, and vitamin B12 deficiencies. The aim of this study to investigate the association between recurrent aphthous stomatitis and hemoglobin, serum ferritin, folic acid, and vitamin B12 deficiency. Patient and Methods: This prospective cross sectional case control clinical study was conducted on 50 patients with recurrent aphthous stomatitis. The control group composed of 50 healthy age and sex-matched subject. The patient demography about family history of recurrent aphthous stomatitis, and smoking was recorded, also the hemoglobin, serum levels of ferritin, folic acid, and vitamin B12 has been investigated. Results: The low hemoglobin was reported in 30% and vitamin B 12 deficiency in 31% of the patient so low hemoglobin and B12 deficiency have significant correlation with recurrent aphthous stomatitis. Patients with low hemoglobin, vitamin B12 deficiency , positive family history, and non smoker have been found to have the highest risk for having recurrent aphthous stomatitis. Conclusion: Recurrent aphthous stomatitis is a multifactorial disease. Positive family history, low hemoglobin level , vitamin B12 deficiency, and nonsmoking status are among the important predisposing factors. Routine hematological screening and tests for iron status, folic acid, and vitamin B12 status should be assessed in all patients with recurrent aphthous stomatitis. https://edj.hmu.edu.krd/index.php/journal/article/view/111HemoglobinFerritinFolic acidVitamin B12Recurrent aphthous stomatitis |
| spellingShingle | Shaheen Ali Ahmed Ali Fakhree Alzubaidee Hematological study of patients with recurrent aphthous stomatitis - Case control study Erbil Dental Journal Hemoglobin Ferritin Folic acid Vitamin B12 Recurrent aphthous stomatitis |
| title | Hematological study of patients with recurrent aphthous stomatitis - Case control study |
| title_full | Hematological study of patients with recurrent aphthous stomatitis - Case control study |
| title_fullStr | Hematological study of patients with recurrent aphthous stomatitis - Case control study |
| title_full_unstemmed | Hematological study of patients with recurrent aphthous stomatitis - Case control study |
| title_short | Hematological study of patients with recurrent aphthous stomatitis - Case control study |
| title_sort | hematological study of patients with recurrent aphthous stomatitis case control study |
| topic | Hemoglobin Ferritin Folic acid Vitamin B12 Recurrent aphthous stomatitis |
| url | https://edj.hmu.edu.krd/index.php/journal/article/view/111 |
| work_keys_str_mv | AT shaheenaliahmed hematologicalstudyofpatientswithrecurrentaphthousstomatitiscasecontrolstudy AT alifakhreealzubaidee hematologicalstudyofpatientswithrecurrentaphthousstomatitiscasecontrolstudy |