Remarkable response to low dose of selpercatinib in a patient with RET-rearranged non-small cell lung cancer

Remarkable response to low dose of selpercatinib in a patient with RET-rearranged non-small cell lung cancer

Chromosomal rearrangements of the RET (rearranged during transfection) gene are detected in approximately 1–2% of non-small cell lung cancers (NSCLC) and have function as oncogenic driver genes. Selpercatinib is a highly effective RET inhibitor for RET-rearranged patients with NSCLC and shows mostly...

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Main Authors: Jun Sakakibara-Konishi, Hirofumi Takahashi, Kenichiro Ito, Tomoo Ikari, Yasuyuki Ikezawa, Hidenori Kitai, Megumi Furuta, Yuta Takashima, Tetsuaki Shoji, Masahide Fukudo, Satoshi Konno
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Non-small cell lung cancer
RET-rearranged lung cancer
Selpercatinib
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007125000127
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