Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY study): study protocol for a multicenter randomized controlled study

Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY study): study protocol for a multicenter randomized controlled study

Abstract Background Endometriosis presents as endometrial tissue growths outside the uterine cavity with its major symptoms including dysmenorrhea and infertility. Progestin preparations, such as dienogest, are the first-line therapy for endometriosis symptoms, but may cause abnormal uterine bleedin...

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Bibliographic Details
Main Authors: Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Trials
Subjects:
Relugolix
Dienogest
Endometriosis
Pain
Visual analog scale
Quality of life
Online Access:https://doi.org/10.1186/s13063-025-08750-9
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