Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation

Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation

Abstract Background Lung cancer patients with comorbid interstitial lung disease (LC-ILD) have an increased risk of developing severe or even fatal radiation pneumonitis after thoracic radiotherapy. However, the underlying mechanisms of its pathogenesis are still inconclusive. No approved biomarker...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiamei Fu, Xinglong Liu, Yuchuan Zhou, Shengnan Zhao, Liang Zeng, Yan Pan, Jianghong Zhang, Kevin M. Prise, Chunlin Shao, Yaping Xu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Radiation Oncology
Subjects:
Animal model
Severe lung injury
Radiation
Interstitial lung disease
Diffuse alveolar damage
Online Access:https://doi.org/10.1186/s13014-025-02596-w
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13014-025-02596-w

Similar Items