Harnessing amino acid pathways to influence myeloid cell function in tumor immunity

Harnessing amino acid pathways to influence myeloid cell function in tumor immunity

Abstract Amino acids are pivotal regulators of immune cell metabolism, signaling pathways, and gene expression. In myeloid cells, these processes underlie their functional plasticity, enabling shifts between pro-inflammatory, anti-inflammatory, pro-tumor, and anti-tumor activities. Within the tumor...

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Bibliographic Details
Main Authors: Jiongli Pan, Yi Lin, Xinyuan Liu, Xiaozhen Zhang, Tingbo Liang, Xueli Bai
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Molecular Medicine
Subjects:
Amino acid metabolism
Myeloid cells
Immunometabolism
Metabolic reprogramming
Cancer immunotherapy
Online Access:https://doi.org/10.1186/s10020-025-01099-4
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https://doi.org/10.1186/s10020-025-01099-4

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