Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma

Bidirectional regulation of reactive oxygen species for radiosensitization in nasopharyngeal carcinoma

Abstract Radiotherapy (RT) is the primary treatment modality for nasopharyngeal carcinoma (NPC). However, the tumor microenvironment (TME)-induced radioresistance often compromises its therapeutic efficacy. Herein, we propose an innovative bidirectional radiosensitization strategy for NPC. Specifica...

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Bibliographic Details
Main Authors: Jie Chen, Chengyu Feng, Yufei Lan, Xiangtian Chen, Zhengqi Peng, Zihan Huang, Ruiqing Wang, Wenxin Zhang, Yingying Ye, Zhilei Mao, Dongyue Pan, Lihua Yang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Nanobiotechnology
Subjects:
DNA hydrogel
Metformin
Copper sulfide
Radiosensitizer
Reactive oxygen species
Online Access:https://doi.org/10.1186/s12951-025-03177-5
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https://doi.org/10.1186/s12951-025-03177-5

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