Is heme biosynthesis influenced the mitochondrial function and cell proliferation in cancer?

Is heme biosynthesis influenced the mitochondrial function and cell proliferation in cancer?

Heme is a compound consisting of an iron (Fe) atom bound to a pyrrole ring forming protoporphyrin IX (PPIX). Protoporphyrin combines with a protein-forming hemoprotein compound that plays an essential role in oxygen-binding and transport as well as in the process of energy production in the mitocho...

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Bibliographic Details
Main Authors: Raisa Nauli, Sri Widia A Jusman
Format: Article
Language:English
Published: Indonesian Society for Biochemistry and Molecular Biology 2022-12-01
Series:Acta Biochimica Indonesiana
Subjects:
heme biosynthesis
hemoprotein
inhibition of heme biosynthesis
cancer cell proliferation
Online Access:https://pbbmi.org/newjurnal/index.php/actabioina/article/view/65
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