Folate alleviated skin inflammation and fibrosis resulting from impaired homocysteine metabolism

Folate alleviated skin inflammation and fibrosis resulting from impaired homocysteine metabolism

Skin fibrosis, characterized by uncontrolled secretion of extracellular matrix (ECM) proteins such as collagen, can lead to excessive scarring and compromised tissue function. Despite the widespread occurrence of fibrotic diseases, effective therapies are lacking. Recent clinical studies have demons...

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Main Authors: Jiefeng Huang, Wuyan Lu, Shenli Zhao, Zixin Cai, Linxiao Li, Zihao Hu, Yu Jiang, Jinyi Deng, Yiming Tang, Chenzhang Shi, Chen Wang, Guangpeng Liu, Shuaijun Li
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Redox Biology
Subjects:
Skin fibrosis
Inflammation
Homocysteine
Folate
JAK2/STAT3 signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172500014X
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