Inhibition of lanosterol synthase linking with MAPK/JNK signaling pathway suppresses endometrial cancer

Abstract Endometrial cancer (EC) is a significant health threat to women, with recurrence after treatment posing a major challenge. While abnormal cholesterol metabolism has been implicated in EC progression, the underlying mechanisms remain unclear. In this study, we identified lanosterol synthase...

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Bibliographic Details
Main Authors: Liangjian Ma, Wunan Huang, Xiaolei Liang, Hongli Li, Wei Yu, Lexin Liu, Yuelin Guan, Chang Liu, Xiangjun Chen, Lidan Hu
Format: Article
Language:English
Published: Nature Publishing Group 2025-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02325-y
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