Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity

Summary: Intracrinology—wherein hormones are synthesized in the organ where they exert their effect without release into circulation—has been described. However, molecular mechanisms of hormone deactivation within intracrine tissue are still largely unknown. The meibomian glands in the eyelids produ...

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Bibliographic Details
Main Authors: Khanh Tien Nguyen Pham, Takahito Miyake, Tomo Suzuki, Shigeru Kinoshita, Yuki Hamada, Hikari Uehara, Mamiko Machida, Takeshi Nakajima, Emi Hasegawa, Masao Doi
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225000689
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