Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi

Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi

Abstract Background Anopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are required to develop novel and more effi...

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Bibliographic Details
Main Authors: Mireia Larrosa-Godall, Joshua X. D. Ang, Philip T. Leftwich, Estela Gonzalez, Lewis Shackleford, Katherine Nevard, Rob Noad, Michelle A. E. Anderson, Luke Alphey
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Parasites & Vectors
Subjects:
CRISPR/Cas9
Gene drive
Doublesex
Malaria
Anopheles stephensi
Online Access:https://doi.org/10.1186/s13071-025-06688-0
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https://doi.org/10.1186/s13071-025-06688-0

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