Sophocarpine inhibits the proliferation and induces apoptosis of glioblastoma cells through regulating the miR-21/PTEN/PI3K/AKT axis

Abstract Sophocarpine (SC) has been reported to suppress tumorigenesis. But the effect of SC on glioblastoma (GBM) is unknown. This study explored the anti-proliferation and pro-apoptosis effects of SC on GBM cells and the molecular mechanism. Different concentrations of SC were used to treat human...

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Bibliographic Details
Main Authors: Feng Si, Qian Wang, Fei Chen, Xiangdong Lu
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-01839-2
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