Triiodothyronine treatment in mice improves stroke outcome and reduces blood–brain barrier damage

Triiodothyronine treatment in mice improves stroke outcome and reduces blood–brain barrier damage

Objective: Thyroid hormones control a variety of processes in the central nervous system and influence its response to different stimuli, such as ischemic stroke. Post-stroke administration of 3,3′,5-triiodo-L-thyronine (T3) has been reported to substantially improve outcomes, but the optimal dosage...

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Main Authors: Daniel Ullrich, Dagmar Führer, Heike Heuer, Steffen Mayerl, Steffen Haupeltshofer, Linda-Isabell Schmitt, Markus Leo, Rebecca D Szepanowski, Tim Hagenacker, Markus Schwaninger, Christoph Kleinschnitz, Friederike Langhauser
Format: Article
Language:English
Published: Bioscientifica 2025-02-01
Series:European Thyroid Journal
Subjects:
blood–brain barrier
ischemic stroke
triiodothyronine
t3
tmcao
Online Access:https://etj.bioscientifica.com/view/journals/etj/14/1/ETJ-24-0143.xml
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