A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context

Summary: Background: Multimorbidity, the presence of two or more conditions in one person, is common but studies are often limited to observational data and single datasets. We address this gap by integrating large-scale primary-care and genetic data from multiple studies to interrogate multimorbid...

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Main Authors: Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:EBioMedicine
Subjects:
Comorbidity
Chronic disease
Multiple long-term conditions
Observational
Genotype
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425000283
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http://www.sciencedirect.com/science/article/pii/S2352396425000283

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