A bidirectional Mendelian randomization study integrating genome-wide association studies, expression quantitative trait locus, and methylation quantitative trait locus data revealed causal relationship between heavy cigarette dependence and Barrett’s esophagus

Background: The association between smoking dependence and the risk of developing Barrett’s esophagus remains unclear. This study aimed to investigate whether a causal relationship exists between smoking dependence and Barrett’s esophagus, using Mendelian randomization analysis. Methods: Two-sample...

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Bibliographic Details
Main Authors: Zhou An, Meichun Zeng, Xianhua Wang
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/20503121251316595
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