Astaxanthin relieves HT22 cells from LPS-induced inflammation and apoptosis by inhibiting oxygen species and regulating the TLR4/MyD88/NFκB signaling pathway

Astaxanthin relieves HT22 cells from LPS-induced inflammation and apoptosis by inhibiting oxygen species and regulating the TLR4/MyD88/NFκB signaling pathway

Astaxanthin exhibits promising anti-inflammatory effects in the treatment of neurodegenerative diseases. Our aim was to explore the mechanisms by which astaxanthin mitigates inflammation associated with these conditions. We treated HT22 cells with lipopolysaccharide (LPS), astaxanthin (ATX), and the...

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Bibliographic Details
Main Authors: Tan Wang, Rongrong Li, Ping Niu, Zhen Wei, Donge Xie, Huorong Huang, Jiayao Pan, Chunshu Rong
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Functional Foods
Subjects:
Neurodegenerative disorders
Astaxanthin
Inflammation
Apoptosis
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464625000180
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