Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model

Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model

Abstract Objective Epidural scar fibrosis commonly leads to functional disability and pain following spinal surgery and is a prevalent manifestation of Failed Back Surgery Syndrome (FBSS). This study aimed to evaluate the use of silver nano-articles (AgNPs) loaded on chitosan (Chi/Ag-NPs) with plate...

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Bibliographic Details
Main Authors: Samah Fouad, Awad Rizk, Esam Mosbah, Mostafa M. Nabeeh, Walaa Awadin, Ayman S. Elmezayyen, Ekramy Elmorsy, Adel Zaghloul
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Neuroscience
Subjects:
Epidural scar fibrosis
Laminectomy
Platelets-rich fibrin
Silver nanoparticle loaded chitosan
Online Access:https://doi.org/10.1186/s12868-025-00929-9
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https://doi.org/10.1186/s12868-025-00929-9

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