The nonlinear cysteine redox dynamics in the i-space: A proteoform-centric theory of redox regulation

The post-translational redox regulation of protein function by cysteine oxidation controls diverse biological processes, from cell division to death. However, most current site-centric paradigms fail to capture the nonlinear and emergent nature of redox regulation in proteins with multiple cysteines...

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Bibliographic Details
Main Authors: James N. Cobley, Panagiotis N. Chatzinikolaou, Cameron A. Schmidt
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000369
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