Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis
Introduction: Arthritis has prompted interest in using physical exercise as therapy. This study assesses the effects of low-, moderate-, and high-intensity exercise on induced arthritis in male Wistar rats. Objective: To evaluate the impact of low-, moderate-, and high-intensity physical exercise o...
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Faculdade de Medicina do ABC
2025-02-01
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| Series: | ABCS Health Sciences |
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| Online Access: | https://nepas.emnuvens.com.br/abcshs/article/view/2317 |
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| author | Alline Mardegan Mioto Daniel Fernando dos Reis Thiago Alves Garcia Guilherme Akio Tamura Ozaki Iara Buriola Trevisan Rodrigo Metzker Pereira Ribeiro Robson Chacon Castoldi José Carlos Silva Camargo Filho |
| author_facet | Alline Mardegan Mioto Daniel Fernando dos Reis Thiago Alves Garcia Guilherme Akio Tamura Ozaki Iara Buriola Trevisan Rodrigo Metzker Pereira Ribeiro Robson Chacon Castoldi José Carlos Silva Camargo Filho |
| author_sort | Alline Mardegan Mioto |
| collection | DOAJ |
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Introduction: Arthritis has prompted interest in using physical exercise as therapy. This study assesses the effects of low-, moderate-, and high-intensity exercise on induced arthritis in male Wistar rats. Objective: To evaluate the impact of low-, moderate-, and high-intensity physical exercise on induced arthritis. Methods: Twenty 60-day-old rats were divided into 5 groups: Control Group Arthritis (GCA), Control Group Placebo (GCP), Group Low Physical Activity (GL), Group Moderate Physical Activity (GM), and Group Intense Physical Activity (GI). The physical activity groups received intra-articular injections of Zymosan in the right knee, followed by aquatic activity, swimming with a dorsal load for 30 minutes, 4 times weekly, for five weeks. Exercise intensity varied: GL 1%, GM 5%, GI 15% of body weight. At the end of the 5th week euthanasia was performed, and soleus muscles were histologically. Group comparisons: one-way ANOVA with Tukey or Kruskal-Wallis with Dunn's post-test, contingent on data homogeneity Levene test. Weight changes: Student’s T-test or ANOVA for repeated measurements, with Bonferroni's post-test for inter-week and first and last-week comparisons within each group. Results: There were no significant differences in inflammatory edema before or after exercise in joint diameter analysis. GI exhibited decreased inflammatory edema in the 3rd week post-activity. GM showed a substantial decrease in the 4th week compared to GL and GI. Post-intervention inflammation did not differ significantly among groups. Conclusion: Varying exercise intensities did not harm any group-induced arthritis in rats.
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| format | Article |
| id | doaj-art-e9d7b0f2653a4f98918571d896ccce3a |
| institution | Kabale University |
| issn | 2318-4965 2357-8114 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Faculdade de Medicina do ABC |
| record_format | Article |
| series | ABCS Health Sciences |
| spelling | doaj-art-e9d7b0f2653a4f98918571d896ccce3a2025-02-10T05:41:12ZengFaculdade de Medicina do ABCABCS Health Sciences2318-49652357-81142025-02-0110.7322/abcshs.2023057.2317Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritisAlline Mardegan Mioto0Daniel Fernando dos Reis1Thiago Alves Garcia2Guilherme Akio Tamura Ozaki3Iara Buriola Trevisan4Rodrigo Metzker Pereira Ribeiro5Robson Chacon Castoldi6José Carlos Silva Camargo Filho7Programa de Pós-Graduação em Ciências do Movimento, Universidade Estadual Paulista (UNESP) – Interunidades (SP), BrazilDepartamento de Educação Física, Universidade do Oeste Paulista (UNOESTE) – Presidente Prudente (SP), BrazilPrograma de Pós-Graduação em Ciências da Cirurgia, Universidade Estadual de Campinas (UNICAMP) – Campinas (SP), BrazilPrograma de Pós-Graduação em Ciências da Cirurgia, Universidade Estadual de Campinas (UNICAMP) – Campinas (SP), BrazilPrograma de Pós-Graduação em Ciências do Movimento, Universidade Estadual Paulista (UNESP) – Interunidades (SP), BrazilDepartamento de Educação Física, Universidade do Oeste Paulista (UNOESTE) – Presidente Prudente (SP), BrazilPrograma de Pós-Graduação em Ciências do Movimento, Universidade Estadual Paulista (UNESP) – Interunidades (SP), Brazil / Programa de Pós-Graduação em Exercício Físico na Promoção da Saúde, Universidade Norte do Paraná (UNOPAR) – Londrina (PR), BrazilPrograma de Pós-Graduação em Ciências do Movimento, Universidade Estadual Paulista (UNESP) – Interunidades (SP), Brazil Introduction: Arthritis has prompted interest in using physical exercise as therapy. This study assesses the effects of low-, moderate-, and high-intensity exercise on induced arthritis in male Wistar rats. Objective: To evaluate the impact of low-, moderate-, and high-intensity physical exercise on induced arthritis. Methods: Twenty 60-day-old rats were divided into 5 groups: Control Group Arthritis (GCA), Control Group Placebo (GCP), Group Low Physical Activity (GL), Group Moderate Physical Activity (GM), and Group Intense Physical Activity (GI). The physical activity groups received intra-articular injections of Zymosan in the right knee, followed by aquatic activity, swimming with a dorsal load for 30 minutes, 4 times weekly, for five weeks. Exercise intensity varied: GL 1%, GM 5%, GI 15% of body weight. At the end of the 5th week euthanasia was performed, and soleus muscles were histologically. Group comparisons: one-way ANOVA with Tukey or Kruskal-Wallis with Dunn's post-test, contingent on data homogeneity Levene test. Weight changes: Student’s T-test or ANOVA for repeated measurements, with Bonferroni's post-test for inter-week and first and last-week comparisons within each group. Results: There were no significant differences in inflammatory edema before or after exercise in joint diameter analysis. GI exhibited decreased inflammatory edema in the 3rd week post-activity. GM showed a substantial decrease in the 4th week compared to GL and GI. Post-intervention inflammation did not differ significantly among groups. Conclusion: Varying exercise intensities did not harm any group-induced arthritis in rats. https://nepas.emnuvens.com.br/abcshs/article/view/2317arthritisexerciseinflammation |
| spellingShingle | Alline Mardegan Mioto Daniel Fernando dos Reis Thiago Alves Garcia Guilherme Akio Tamura Ozaki Iara Buriola Trevisan Rodrigo Metzker Pereira Ribeiro Robson Chacon Castoldi José Carlos Silva Camargo Filho Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis ABCS Health Sciences arthritis exercise inflammation |
| title | Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis |
| title_full | Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis |
| title_fullStr | Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis |
| title_full_unstemmed | Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis |
| title_short | Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis |
| title_sort | effects of low moderate and high intensity aquatic exercise on joint edema in induced rat knee arthritis |
| topic | arthritis exercise inflammation |
| url | https://nepas.emnuvens.com.br/abcshs/article/view/2317 |
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