A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study
Background and Aim: Cranial cruciate ligament (CrCL) injuries are a prevalent orthopedic issue in dogs, typically managed through surgical interventions such as tibial plateau leveling osteotomy and tibial tuberosity advancement. However, these techniques have limitations, including high costs and e...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Veterinary World
2025-01-01
|
| Series: | Veterinary World |
| Subjects: | |
| Online Access: | https://www.veterinaryworld.org/Vol.18/January-2025/23.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825206198328098816 |
|---|---|
| author | Mousa H. Daradka Mays A. Malkawi Zuhair Banni Ismail1 Hanan M. Hammouri Mahmoud A. Abu-Abeeleh Saba A. Rihani |
| author_facet | Mousa H. Daradka Mays A. Malkawi Zuhair Banni Ismail1 Hanan M. Hammouri Mahmoud A. Abu-Abeeleh Saba A. Rihani |
| author_sort | Mousa H. Daradka |
| collection | DOAJ |
| description | Background and Aim: Cranial cruciate ligament (CrCL) injuries are a prevalent orthopedic issue in dogs, typically managed through surgical interventions such as tibial plateau leveling osteotomy and tibial tuberosity advancement. However, these techniques have limitations, including high costs and extended recovery periods. This study introduces an innovative CrCL repair method employing an autologous lateral digital extensor muscle tendon graft and evaluates the effects of platelet-rich plasma (PRP) on tissue healing.
Materials and Methods: Twenty-four healthy, male, local-breed dogs were divided into two groups. Group A underwent the surgical procedure without PRP, while Group B received intra-articular PRP during surgery. Outcomes were evaluated through clinical assessments of lameness, post-operative complications, and histological analysis over 10, 20, 30, and 40 days.
Results: The PRP-treated group demonstrated statistically significant improvements in post-operative complication scores (p = 0.0025) and histological outcomes (p = 0.0002). However, graft maturation was unaffected by PRP treatment but improved over time (p = 0.0013). PRP-treated dogs exhibited faster recovery and enhanced tissue regeneration, with reduced inflammation and improved graft-bone attachment.
Conclusion: This novel surgical approach demonstrates significant potential for improving outcomes in CrCL repair by combining autologous tendon grafting with PRP. The technique offers reduced complications and enhanced healing, providing a promising alternative to traditional methods. Further studies are recommended to validate its efficacy in clinical settings. |
| format | Article |
| id | doaj-art-ea2fe576742142c5a082cb02ed94ca67 |
| institution | Kabale University |
| issn | 0972-8988 2231-0916 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj-art-ea2fe576742142c5a082cb02ed94ca672025-02-07T13:01:00ZengVeterinary WorldVeterinary World0972-89882231-09162025-01-0118121021910.14202/vetworld.2025.210-219A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental studyMousa H. Daradka0https://orcid.org/0000-0002-8443-9023Mays A. Malkawi1https://orcid.org/0000-0001-9091-572XZuhair Banni Ismail12https://orcid.org/0000-0002-7267-8270Hanan M. Hammouri3https://orcid.org/0000-0001-7009-1022Mahmoud A. Abu-Abeeleh4https://orcid.org/0000-0001-9349-385XSaba A. Rihani5https://orcid.org/0009-0001-3712-3034Department of Clinical Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.Department of Clinical Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.Department of Clinical Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.Department of Mathematics and Statistics, Faculty of Science and Arts, Jordan University of Science and Technology. P.O. Box 3030, Irbid, 22110, Jordan.Deparment of General Surgery, Faculty of Medicine, The University of Jordan.P.O.Box 13857, Amman, 11942, Jordan.Department of Clinical Veterinary Medical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.Background and Aim: Cranial cruciate ligament (CrCL) injuries are a prevalent orthopedic issue in dogs, typically managed through surgical interventions such as tibial plateau leveling osteotomy and tibial tuberosity advancement. However, these techniques have limitations, including high costs and extended recovery periods. This study introduces an innovative CrCL repair method employing an autologous lateral digital extensor muscle tendon graft and evaluates the effects of platelet-rich plasma (PRP) on tissue healing. Materials and Methods: Twenty-four healthy, male, local-breed dogs were divided into two groups. Group A underwent the surgical procedure without PRP, while Group B received intra-articular PRP during surgery. Outcomes were evaluated through clinical assessments of lameness, post-operative complications, and histological analysis over 10, 20, 30, and 40 days. Results: The PRP-treated group demonstrated statistically significant improvements in post-operative complication scores (p = 0.0025) and histological outcomes (p = 0.0002). However, graft maturation was unaffected by PRP treatment but improved over time (p = 0.0013). PRP-treated dogs exhibited faster recovery and enhanced tissue regeneration, with reduced inflammation and improved graft-bone attachment. Conclusion: This novel surgical approach demonstrates significant potential for improving outcomes in CrCL repair by combining autologous tendon grafting with PRP. The technique offers reduced complications and enhanced healing, providing a promising alternative to traditional methods. Further studies are recommended to validate its efficacy in clinical settings.https://www.veterinaryworld.org/Vol.18/January-2025/23.pdfcaninecranial cruciate ligamentprptendon grafttissue healing |
| spellingShingle | Mousa H. Daradka Mays A. Malkawi Zuhair Banni Ismail1 Hanan M. Hammouri Mahmoud A. Abu-Abeeleh Saba A. Rihani A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study Veterinary World canine cranial cruciate ligament prp tendon graft tissue healing |
| title | A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study |
| title_full | A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study |
| title_fullStr | A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study |
| title_full_unstemmed | A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study |
| title_short | A novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet-rich plasma: A preliminary experimental study |
| title_sort | novel surgical technique for cranial cruciate ligament repair in dogs using autologous lateral digital extensor muscle tendon graft combined with platelet rich plasma a preliminary experimental study |
| topic | canine cranial cruciate ligament prp tendon graft tissue healing |
| url | https://www.veterinaryworld.org/Vol.18/January-2025/23.pdf |
| work_keys_str_mv | AT mousahdaradka anovelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT maysamalkawi anovelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT zuhairbanniismail1 anovelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT hananmhammouri anovelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT mahmoudaabuabeeleh anovelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT sabaarihani anovelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT mousahdaradka novelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT maysamalkawi novelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT zuhairbanniismail1 novelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT hananmhammouri novelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT mahmoudaabuabeeleh novelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy AT sabaarihani novelsurgicaltechniqueforcranialcruciateligamentrepairindogsusingautologouslateraldigitalextensormuscletendongraftcombinedwithplateletrichplasmaapreliminaryexperimentalstudy |